| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30088483 | HIV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
| TVIS30063793 | HIV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
| TVIS30063794 | HIV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
| TVIS20008491 | HPV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
| TVIS20043606 | HPV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
| TVIS20023643 | HPV | ENSG00000164270.19 | protein_coding | HTR4 | No | No | 3360 | A0A2D3FAF9 Q13639 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR4 |
|---|---|
| DrugBank ID | DB01233 |
| Drug Name | Metoclopramide |
| Target ID | BE0000084 |
| UniProt ID | Q13639 |
| Regulation Type | agonist |
| PubMed IDs | 18948374; 21278804; 21585331 |
| Citations | Guillemot J, Compagnon P, Cartier D, Thouennon E, Bastard C, Lihrmann I, Pichon P, Thuillez C, Plouin PF, Bertherat J, Anouar Y, Kuhn JM, Yon L, Lefebvre H: Metoclopramide stimulates catecholamine- and granin-derived peptide secretion from pheochromocytoma cells through activation of serotonin type 4 (5-HT4) receptors. Endocr Relat Cancer. 2009 Mar;16(1):281-90. doi: 10.1677/ERC-08-0190. Epub 2008 Oct 23.@@Lee A, Kuo B: Metoclopramide in the treatment of diabetic gastroparesis. Expert Rev Endocrinol Metab. 2010;5(5):653-662.@@Bartolini A, Di Cesare Mannelli L, Ghelardini C: Analgesic and antineuropathic drugs acting through central cholinergic mechanisms. Recent Pat CNS Drug Discov. 2011 May 1;6(2):119-40. |
| Groups | Approved; Investigational |
| Direct Classification | Aminophenyl ethers |
| SMILES | CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC |
| Pathways | |
| PharmGKB | PA450475 |
| ChEMBL | CHEMBL86 |
