| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30023045 | HIV | ENSG00000182866.18 | protein_coding | LCK | Yes | No | 3932 | A0A0S2Z3Y4 A0A0S2Z3Y8 P06239 Q573B4 |
| TVIS30023046 | HIV | ENSG00000182866.18 | protein_coding | LCK | Yes | No | 3932 | A0A0S2Z3Y4 A0A0S2Z3Y8 P06239 Q573B4 |
| TVIS30023047 | HIV | ENSG00000182866.18 | protein_coding | LCK | Yes | No | 3932 | A0A0S2Z3Y4 A0A0S2Z3Y8 P06239 Q573B4 |
| TVIS30023048 | HIV | ENSG00000182866.18 | protein_coding | LCK | Yes | No | 3932 | A0A0S2Z3Y4 A0A0S2Z3Y8 P06239 Q573B4 |
| TVIS30023049 | HIV | ENSG00000182866.18 | protein_coding | LCK | Yes | No | 3932 | A0A0S2Z3Y4 A0A0S2Z3Y8 P06239 Q573B4 |
| TVIS44018658 | HTLV-1 | ENSG00000182866.18 | protein_coding | LCK | Yes | No | 3932 | A0A0S2Z3Y4 A0A0S2Z3Y8 P06239 Q573B4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | LCK |
|---|---|
| DrugBank ID | DB03023 |
| Drug Name | 1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine |
| Target ID | BE0000842 |
| UniProt ID | P06239 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental |
| Direct Classification | Phenylpyrazoles |
| SMILES | CC(C)(C)N1[NH+]=C(C2=C1N=CN=C2N)C1=CC=C(Cl)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL |
