| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10005318 | HBV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS30010961 | HIV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS20004407 | HPV | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS44011440 | HTLV-1 | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
| TVIS44011749 | HTLV-1 | ENSG00000196591.12 | protein_coding | HDAC2 | Yes | No | 3066 | Q92769 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HDAC2 |
|---|---|
| DrugBank ID | DB00641 |
| Drug Name | Simvastatin |
| Target ID | BE0002366 |
| UniProt ID | Q92769 |
| Regulation Type | inhibitor |
| PubMed IDs | 18381445 |
| Citations | Lin YC, Lin JH, Chou CW, Chang YF, Yeh SH, Chen CC: Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2. Cancer Res. 2008 Apr 1;68(7):2375-83. doi: 10.1158/0008-5472.CAN-07-5807. |
| Groups | Approved |
| Direct Classification | Delta valerolactones |
| SMILES | [H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)C(C)(C)CC |
| Pathways | Simvastatin Action Pathway |
| PharmGKB | PA451363 |
| ChEMBL | CHEMBL1064 |
