Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10005318HBVENSG00000196591.12protein_codingHDAC2YesNo3066Q92769
TVIS30010961HIVENSG00000196591.12protein_codingHDAC2YesNo3066Q92769
TVIS20004407HPVENSG00000196591.12protein_codingHDAC2YesNo3066Q92769
TVIS44011440HTLV-1ENSG00000196591.12protein_codingHDAC2YesNo3066Q92769
TVIS44011749HTLV-1ENSG00000196591.12protein_codingHDAC2YesNo3066Q92769
TCGA Plot Options
Drug Information
GeneHDAC2
DrugBank IDDB01076
Drug NameAtorvastatin
Target IDBE0002366
UniProt IDQ92769
Regulation Typeinhibitor
PubMed IDs18381445
CitationsLin YC, Lin JH, Chou CW, Chang YF, Yeh SH, Chen CC: Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2. Cancer Res. 2008 Apr 1;68(7):2375-83. doi: 10.1158/0008-5472.CAN-07-5807.
GroupsApproved
Direct ClassificationDiphenylpyrroles
SMILESCC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
Pathways
PharmGKBPA448500
ChEMBLCHEMBL1487