Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10005318HBVENSG00000196591.12protein_codingHDAC2YesNo3066Q92769
TVIS30010961HIVENSG00000196591.12protein_codingHDAC2YesNo3066Q92769
TVIS20004407HPVENSG00000196591.12protein_codingHDAC2YesNo3066Q92769
TVIS44011440HTLV-1ENSG00000196591.12protein_codingHDAC2YesNo3066Q92769
TVIS44011749HTLV-1ENSG00000196591.12protein_codingHDAC2YesNo3066Q92769
TCGA Plot Options
Drug Information
GeneHDAC2
DrugBank IDDB01223
Drug NameAminophylline
Target IDBE0002366
UniProt IDQ92769
Regulation Typeactivator
PubMed IDs12070353
CitationsIto K, Lim S, Caramori G, Cosio B, Chung KF, Adcock IM, Barnes PJ: A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8921-6. Epub 2002 Jun 17.
GroupsApproved
Direct ClassificationMonoalkylamines
SMILESNCCN.CN1C2=C(NC=N2)C(=O)N(C)C1=O.CN1C2=C(NC=N2)C(=O)N(C)C1=O
Pathways
PharmGKBPA164781029
ChEMBLCHEMBL1370561