VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS30004395 | HIV | ENSG00000167325.15 | protein_coding | RRM1 | No | No | 6240 | E9PL69 P23921 |
TVIS30005737 | HIV | ENSG00000167325.15 | protein_coding | RRM1 | No | No | 6240 | E9PL69 P23921 |
TVIS30028946 | HIV | ENSG00000167325.15 | protein_coding | RRM1 | No | No | 6240 | E9PL69 P23921 |
TVIS30028947 | HIV | ENSG00000167325.15 | protein_coding | RRM1 | No | No | 6240 | E9PL69 P23921 |
TVIS30028948 | HIV | ENSG00000167325.15 | protein_coding | RRM1 | No | No | 6240 | E9PL69 P23921 |
TVIS30028949 | HIV | ENSG00000167325.15 | protein_coding | RRM1 | No | No | 6240 | E9PL69 P23921 |
TVIS30028950 | HIV | ENSG00000167325.15 | protein_coding | RRM1 | No | No | 6240 | E9PL69 P23921 |
TVIS30028951 | HIV | ENSG00000167325.15 | protein_coding | RRM1 | No | No | 6240 | E9PL69 P23921 |
TVIS30028952 | HIV | ENSG00000167325.15 | protein_coding | RRM1 | No | No | 6240 | E9PL69 P23921 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | RRM1 |
---|---|
DrugBank ID | DB01073 |
Drug Name | Fludarabine |
Target ID | BE0000325 |
UniProt ID | P23921 |
Regulation Type | inhibitor |
PubMed IDs | 17139284; 17016423; 19519505; 19325518 |
Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Lech-Maranda E, Korycka A, Robak T: Clofarabine as a novel nucleoside analogue approved to treat patients with haematological malignancies: mechanism of action and clinical activity. Mini Rev Med Chem. 2009 Jun;9(7):805-12.@@Robak T, Korycka A, Lech-Maranda E, Robak P: Current status of older and new purine nucleoside analogues in the treatment of lymphoproliferative diseases. Molecules. 2009 Mar 23;14(3):1183-226. doi: 10.3390/molecules14031183. |
Groups | Approved |
Direct Classification | Purine nucleosides |
SMILES | NC1=NC(F)=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O |
Pathways | |
PharmGKB | PA449655 |
ChEMBL | CHEMBL1568 |