Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS42000535EBVENSG00000196557.14protein_codingCACNA1HNoNo8912A0A1W2PQW2
O95180
TVIS30079906HIVENSG00000196557.14protein_codingCACNA1HNoNo8912A0A1W2PQW2
O95180
TVIS30083071HIVENSG00000196557.14protein_codingCACNA1HNoNo8912A0A1W2PQW2
O95180
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Drug Information
GeneCACNA1H
DrugBank IDDB01023
Drug NameFelodipine
Target IDBE0000864
UniProt IDO95180
Regulation Typeinhibitor
PubMed IDs1281221; 18974361
CitationsCohen CJ, Spires S, Van Skiver D: Block of T-type Ca channels in guinea pig atrial cells by antiarrhythmic agents and Ca channel antagonists. J Gen Physiol. 1992 Oct;100(4):703-28.@@Perez-Reyes E, Van Deusen AL, Vitko I: Molecular pharmacology of human Cav3.2 T-type Ca2+ channels: block by antihypertensives, antiarrhythmics, and their analogs. J Pharmacol Exp Ther. 2009 Feb;328(2):621-7. doi: 10.1124/jpet.108.145672. Epub 2008 Oct 30.
GroupsApproved; Investigational
Direct ClassificationDihydropyridinecarboxylic acids and derivatives
SMILESCCOC(=O)C1=C(C)NC(C)=C(C1C1=C(Cl)C(Cl)=CC=C1)C(=O)OC
PathwaysFelodipine Metabolism Pathway; Felodipine Action Pathway
PharmGKBPA449591
ChEMBLCHEMBL1480