Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS42000535EBVENSG00000196557.14protein_codingCACNA1HNoNo8912A0A1W2PQW2
O95180
TVIS30079906HIVENSG00000196557.14protein_codingCACNA1HNoNo8912A0A1W2PQW2
O95180
TVIS30083071HIVENSG00000196557.14protein_codingCACNA1HNoNo8912A0A1W2PQW2
O95180
TCGA Plot Options
Drug Information
GeneCACNA1H
DrugBank IDDB01054
Drug NameNitrendipine
Target IDBE0000864
UniProt IDO95180
Regulation Typeinhibitor
PubMed IDs18974361; 1846597
CitationsPerez-Reyes E, Van Deusen AL, Vitko I: Molecular pharmacology of human Cav3.2 T-type Ca2+ channels: block by antihypertensives, antiarrhythmics, and their analogs. J Pharmacol Exp Ther. 2009 Feb;328(2):621-7. doi: 10.1124/jpet.108.145672. Epub 2008 Oct 30.@@Regulla S, Schneider T, Nastainczyk W, Meyer HE, Hofmann F: Identification of the site of interaction of the dihydropyridine channel blockers nitrendipine and azidopine with the calcium-channel alpha 1 subunit. EMBO J. 1991 Jan;10(1):45-9.
GroupsApproved; Investigational
Direct ClassificationDihydropyridinecarboxylic acids and derivatives
SMILESCCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC
PathwaysNitrendipine Action Pathway
PharmGKBPA146096020
ChEMBLCHEMBL475534