Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNMA1 |
|---|---|
| DrugBank ID | DB00999 |
| Drug Name | Hydrochlorothiazide |
| Target ID | BE0000553 |
| UniProt ID | Q12791 |
| Regulation Type | inhibitor |
| PubMed IDs | 9856976 |
| Citations | Pickkers P, Hughes AD, Russel FG, Thien T, Smits P: Thiazide-induced vasodilation in humans is mediated by potassium channel activation. Hypertension. 1998 Dec;32(6):1071-6. doi: 10.1161/01.hyp.32.6.1071. |
| Groups | Approved; Vet_approved |
| Direct Classification | 1,2,4-benzothiadiazine-1,1-dioxides |
| SMILES | NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1 |
| Pathways | Hydrochlorothiazide Action Pathway |
| PharmGKB | PA449899 |
| ChEMBL | CHEMBL435 |
