| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44015196 | HTLV-1 | ENSG00000151067.23 | protein_coding | CACNA1C | No | No | 775 | A0A0A0MR67 A0A0A0MSA1 F5H522 Q13936 Q5V9X9 |
| TVIS44002399 | HTLV-1 | ENSG00000151067.23 | protein_coding | CACNA1C | No | No | 775 | A0A0A0MR67 A0A0A0MSA1 F5H522 Q13936 Q5V9X9 |
| TVIS44010875 | HTLV-1 | ENSG00000151067.23 | protein_coding | CACNA1C | No | No | 775 | A0A0A0MR67 A0A0A0MSA1 F5H522 Q13936 Q5V9X9 |
| TVIS44034377 | HTLV-1 | ENSG00000151067.23 | protein_coding | CACNA1C | No | No | 775 | A0A0A0MR67 A0A0A0MSA1 F5H522 Q13936 Q5V9X9 |
| TVIS44049463 | HTLV-1 | ENSG00000151067.23 | protein_coding | CACNA1C | No | No | 775 | A0A0A0MR67 A0A0A0MSA1 F5H522 Q13936 Q5V9X9 |
| TVIS44035588 | HTLV-1 | ENSG00000151067.23 | protein_coding | CACNA1C | No | No | 775 | A0A0A0MR67 A0A0A0MSA1 F5H522 Q13936 Q5V9X9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1C |
|---|---|
| DrugBank ID | DB00381 |
| Drug Name | Amlodipine |
| Target ID | BE0000430 |
| UniProt ID | Q13936 |
| Regulation Type | inhibitor |
| PubMed IDs | 16322774; 27556947 |
| Citations | Bodi I, Mikala G, Koch SE, Akhter SA, Schwartz A: The L-type calcium channel in the heart: the beat goes on. J Clin Invest. 2005 Dec;115(12):3306-17. doi: 10.1172/JCI27167.@@Tang L, Gamal El-Din TM, Swanson TM, Pryde DC, Scheuer T, Zheng N, Catterall WA: Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature. 2016 Sep 1;537(7618):117-121. doi: 10.1038/nature19102. Epub 2016 Aug 24. |
| Groups | Approved |
| Direct Classification | Dihydropyridinecarboxylic acids and derivatives |
| SMILES | CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC |
| Pathways | Amlodipine Action Pathway |
| PharmGKB | PA448388 |
| ChEMBL | CHEMBL1491 |
