| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20020006 | HPV | ENSG00000179097.7 | protein_coding | HTR1F | No | No | 3355 | P30939 |
| TVIS20020007 | HPV | ENSG00000179097.7 | protein_coding | HTR1F | No | No | 3355 | P30939 |
| TVIS44019173 | HTLV-1 | ENSG00000179097.7 | protein_coding | HTR1F | No | No | 3355 | P30939 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR1F |
|---|---|
| DrugBank ID | DB00952 |
| Drug Name | Naratriptan |
| Target ID | BE0000460 |
| UniProt ID | P30939 |
| Regulation Type | agonist |
| PubMed IDs | 11752352; 14725972; 11152011; 12463278; 15320857; 14614913; 12434581 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Hoskin KL, Lambert GA, Donaldson C, Zagami AS: The 5-hydroxytryptamine1B/1D/1F receptor agonists eletriptan and naratriptan inhibit trigeminovascular input to the nucleus tractus solitarius in the cat. Brain Res. 2004 Feb 13;998(1):91-9.@@Tfelt-Hansen P, De Vries P, Saxena PR: Triptans in migraine: a comparative review of pharmacology, pharmacokinetics and efficacy. Drugs. 2000 Dec;60(6):1259-87.@@Massiou H: Naratriptan. Curr Med Res Opin. 2001;17 Suppl 1:s51-3.@@Villalon CM, Centurion D, Valdivia LF, de Vries P, Saxena PR: Migraine: pathophysiology, pharmacology, treatment and future trends. Curr Vasc Pharmacol. 2003 Mar;1(1):71-84.@@Goadsby PJ, Classey JD: Evidence for serotonin (5-HT)1B, 5-HT1D and 5-HT1F receptor inhibitory effects on trigeminal neurons with craniovascular input. Neuroscience. 2003;122(2):491-8.@@Villalon CM, Centurion D, Valdivia LF, De Vries P, Saxena PR: An introduction to migraine: from ancient treatment to functional pharmacology and antimigraine therapy. Proc West Pharmacol Soc. 2002;45:199-210. |
| Groups | Approved; Investigational |
| Direct Classification | 3-alkylindoles |
| SMILES | CNS(=O)(=O)CCC1=CC2=C(NC=C2C2CCN(C)CC2)C=C1 |
| Pathways | |
| PharmGKB | PA450597 |
| ChEMBL | CHEMBL1278 |
