| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20020006 | HPV | ENSG00000179097.7 | protein_coding | HTR1F | No | No | 3355 | P30939 |
| TVIS20020007 | HPV | ENSG00000179097.7 | protein_coding | HTR1F | No | No | 3355 | P30939 |
| TVIS44019173 | HTLV-1 | ENSG00000179097.7 | protein_coding | HTR1F | No | No | 3355 | P30939 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR1F |
|---|---|
| DrugBank ID | DB00953 |
| Drug Name | Rizatriptan |
| Target ID | BE0000460 |
| UniProt ID | P30939 |
| Regulation Type | agonist |
| PubMed IDs | 11752352; 15320857; 12434581; 9718276; 14614913 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Villalon CM, Centurion D, Valdivia LF, de Vries P, Saxena PR: Migraine: pathophysiology, pharmacology, treatment and future trends. Curr Vasc Pharmacol. 2003 Mar;1(1):71-84.@@Villalon CM, Centurion D, Valdivia LF, De Vries P, Saxena PR: An introduction to migraine: from ancient treatment to functional pharmacology and antimigraine therapy. Proc West Pharmacol Soc. 2002;45:199-210.@@Wainscott DB, Johnson KW, Phebus LA, Schaus JM, Nelson DL: Human 5-HT1F receptor-stimulated [35S]GTPgammaS binding: correlation with inhibition of guinea pig dural plasma protein extravasation. Eur J Pharmacol. 1998 Jul 3;352(1):117-24.@@Goadsby PJ, Classey JD: Evidence for serotonin (5-HT)1B, 5-HT1D and 5-HT1F receptor inhibitory effects on trigeminal neurons with craniovascular input. Neuroscience. 2003;122(2):491-8. |
| Groups | Approved |
| Direct Classification | Tryptamines and derivatives |
| SMILES | CN(C)CCC1=CNC2=C1C=C(CN1C=NC=N1)C=C2 |
| Pathways | |
| PharmGKB | PA451264 |
| ChEMBL | CHEMBL905 |
