| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10046896 | HBV | ENSG00000115705.22 | protein_coding | TPO | No | No | 7173 | P07202 Q502Y3 Q6P534 |
| TVIS20007279 | HPV | ENSG00000115705.22 | protein_coding | TPO | No | No | 7173 | P07202 Q502Y3 Q6P534 |
| TVIS20005425 | HPV | ENSG00000115705.22 | protein_coding | TPO | No | No | 7173 | P07202 Q502Y3 Q6P534 |
| TVIS20042386 | HPV | ENSG00000115705.22 | protein_coding | TPO | No | No | 7173 | P07202 Q502Y3 Q6P534 |
| TVIS20040873 | HPV | ENSG00000115705.22 | protein_coding | TPO | No | No | 7173 | P07202 Q502Y3 Q6P534 |
| TVIS20023692 | HPV | ENSG00000115705.22 | protein_coding | TPO | No | No | 7173 | P07202 Q502Y3 Q6P534 |
| TVIS44015773 | HTLV-1 | ENSG00000115705.22 | protein_coding | TPO | No | No | 7173 | P07202 Q502Y3 Q6P534 |
| TVIS44008995 | HTLV-1 | ENSG00000115705.22 | protein_coding | TPO | No | No | 7173 | P07202 Q502Y3 Q6P534 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TPO |
|---|---|
| DrugBank ID | DB11496 |
| Drug Name | 2-mercaptobenzothiazole |
| Target ID | BE0000507 |
| UniProt ID | P07202 |
| Regulation Type | inhibitor |
| PubMed IDs | 26865668 |
| Citations | Leonard JA, Tan YM, Gilbert M, Isaacs K, El-Masri H: Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling. Toxicol Sci. 2016 May;151(1):57-70. doi: 10.1093/toxsci/kfw022. Epub 2016 Feb 10. |
| Groups | Approved; Experimental; Vet_approved |
| Direct Classification | Benzothiazoles |
| SMILES | S=C1NC2=C(S1)C=CC=C2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL111654 |
