| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30054123 | HIV | ENSG00000101204.18 | protein_coding | CHRNA4 | No | No | 1137 | P43681 Q4VAQ3 |
| TVIS20067223 | HPV | ENSG00000101204.18 | protein_coding | CHRNA4 | No | No | 1137 | P43681 Q4VAQ3 |
| TVIS20037058 | HPV | ENSG00000101204.18 | protein_coding | CHRNA4 | No | No | 1137 | P43681 Q4VAQ3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHRNA4 |
|---|---|
| DrugBank ID | DB00564 |
| Drug Name | Carbamazepine |
| Target ID | BE0000849 |
| UniProt ID | P43681 |
| Regulation Type | |
| PubMed IDs | 12110613; 20561518; 15309115 |
| Citations | Ortells MO, Barrantes GE: Molecular modelling of the interactions of carbamazepine and a nicotinic receptor involved in the autosomal dominant nocturnal frontal lobe epilepsy. Br J Pharmacol. 2002 Jul;136(6):883-95. doi: 10.1038/sj.bjp.0704786.@@Di Resta C, Ambrosi P, Curia G, Becchetti A: Effect of carbamazepine and oxcarbazepine on wild-type and mutant neuronal nicotinic acetylcholine receptors linked to nocturnal frontal lobe epilepsy. Eur J Pharmacol. 2010 Sep 15;643(1):13-20. doi: 10.1016/j.ejphar.2010.05.063. Epub 2010 Jun 16.@@Bertrand D: Neuronal Nicotinic Acetylcholine Receptors and Epilepsy. Epilepsy Curr. 2002 Nov;2(6):191-193. doi: 10.1046/j.1535-7597.2002.00072.x. |
| Groups | Approved; Investigational |
| Direct Classification | Dibenzazepines |
| SMILES | NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12 |
| Pathways | Carbamazepine Metabolism Pathway |
| PharmGKB | PA448785 |
| ChEMBL | CHEMBL108 |
