| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20050998 | HPV | ENSG00000122025.15 | protein_coding | FLT3 | Yes | No | 2322 | P36888 |
| TVIS20065483 | HPV | ENSG00000122025.15 | protein_coding | FLT3 | Yes | No | 2322 | P36888 |
| TVIS44031243 | HTLV-1 | ENSG00000122025.15 | protein_coding | FLT3 | Yes | No | 2322 | P36888 |
| TVIS44008044 | HTLV-1 | ENSG00000122025.15 | protein_coding | FLT3 | Yes | No | 2322 | P36888 |
| TVIS44020668 | HTLV-1 | ENSG00000122025.15 | protein_coding | FLT3 | Yes | No | 2322 | P36888 |
| TVIS44036283 | HTLV-1 | ENSG00000122025.15 | protein_coding | FLT3 | Yes | No | 2322 | P36888 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FLT3 |
|---|---|
| DrugBank ID | DB12978 |
| Drug Name | Pexidartinib |
| Target ID | BE0000147 |
| UniProt ID | P36888 |
| Regulation Type | inhibitor |
| PubMed IDs | 28716061 |
| Citations | Cannarile MA, Weisser M, Jacob W, Jegg AM, Ries CH, Ruttinger D: Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy. J Immunother Cancer. 2017 Jul 18;5(1):53. doi: 10.1186/s40425-017-0257-y. |
| Groups | Approved; Investigational |
| Direct Classification | Pyrrolopyridines |
| SMILES | FC(F)(F)C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C34)C=C2)C=N1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3813873 |
