| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017714 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10015036 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10030720 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10035479 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10018975 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10049265 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS20002315 | HPV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS44045260 | HTLV-1 | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS44045289 | HTLV-1 | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PLG |
|---|---|
| DrugBank ID | DB00013 |
| Drug Name | Urokinase |
| Target ID | BE0000211 |
| UniProt ID | P00747 |
| Regulation Type | activator |
| PubMed IDs | 12658774; 12666133; 12719778; 12720300; 12745435; 11752352 |
| Citations | Zhang X, Zhou H, Shen G, Liu Z, Hu Y, Wei W, Song S: Study on the mechanism of the annexin II-mediated co-assembly of t-PA and plasminogen. J Huazhong Univ Sci Technolog Med Sci. 2002;22(1):21-3, 76.@@Lopez-Alemany R, Longstaff C, Hawley S, Mirshahi M, Fabregas P, Jardi M, Merton E, Miles LA, Felez J: Inhibition of cell surface mediated plasminogen activation by a monoclonal antibody against alpha-Enolase. Am J Hematol. 2003 Apr;72(4):234-42.@@Hashimoto M, Oiwa K, Matsuo O, Ueshima S, Okada K, Okada Y, Okamoto S, Giddings JC, Yamamoto J: Suppression of argatroban-induced endogenous thrombolysis by PKSI-527, and antibodies to TPA and UPA, evaluated in a rat arterial thrombolysis model. Thromb Haemost. 2003 May;89(5):820-5.@@Guda K, Claffey KP, Dong M, Nambiar PR, Rosenberg DW: Defective processing of the transforming growth factor-beta1 in azoxymethane-induced mouse colon tumors. Mol Carcinog. 2003 May;37(1):51-9.@@Chang H, Shyu KG, Lin S, Wang BW, Liu YC, Lee CC: Cell adhesion induces the plasminogen activator inhibitor-1 gene expression through phosphatidylinositol 3-kinase/Akt activation in anchorage dependent cells. Cell Commun Adhes. 2002 Sep-Dec;9(5-6):239-47.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational; Withdrawn |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | Urokinase Action Pathway |
| PharmGKB | PA451836 |
| ChEMBL | CHEMBL1201420 |
