| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017714 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10015036 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10030720 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10035479 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10018975 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10049265 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS20002315 | HPV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS44045260 | HTLV-1 | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS44045289 | HTLV-1 | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | PLG |
|---|---|
| DrugBank ID | DB00015 |
| Drug Name | Reteplase |
| Target ID | BE0000211 |
| UniProt ID | P00747 |
| Regulation Type | activator |
| PubMed IDs | 17963464; 18673235; 19436656; 11752352 |
| Citations | Hilleman DE, Tsikouris JP, Seals AA, Marmur JD: Fibrinolytic agents for the management of ST-segment elevation myocardial infarction. Pharmacotherapy. 2007 Nov;27(11):1558-70.@@Longstaff C, Williams S, Thelwell C: Fibrin binding and the regulation of plasminogen activators during thrombolytic therapy. Cardiovasc Hematol Agents Med Chem. 2008 Jul;6(3):212-23.@@Melandri G, Vagnarelli F, Calabrese D, Semprini F, Nanni S, Branzi A: Review of tenecteplase (TNKase) in the treatment of acute myocardial infarction. Vasc Health Risk Manag. 2009;5(1):249-56. Epub 2009 Apr 8.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | Reteplase Action Pathway |
| PharmGKB | PA164743728 |
| ChEMBL | CHEMBL2107885 |
