| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20017104 | HPV | ENSG00000134853.12 | protein_coding | PDGFRA | Yes | No | 5156 | P16234 |
| TVIS20058559 | HPV | ENSG00000134853.12 | protein_coding | PDGFRA | Yes | No | 5156 | P16234 |
| TVIS44048880 | HTLV-1 | ENSG00000134853.12 | protein_coding | PDGFRA | Yes | No | 5156 | P16234 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDGFRA |
|---|---|
| DrugBank ID | DB01268 |
| Drug Name | Sunitinib |
| Target ID | BE0000852 |
| UniProt ID | P16234 |
| Regulation Type | inhibitor |
| PubMed IDs | 16638875 |
| Citations | Prenen H, Cools J, Mentens N, Folens C, Sciot R, Schoffski P, Van Oosterom A, Marynen P, Debiec-Rychter M: Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate. Clin Cancer Res. 2006 Apr 15;12(8):2622-7. |
| Groups | Approved; Investigational |
| Direct Classification | Indolines |
| SMILES | CCN(CC)CCNC(=O)C1=C(C)NC(C=C2/C(=O)NC3=C2C=C(F)C=C3)=C1C |
| Pathways | |
| PharmGKB | PA162372840 |
| ChEMBL | CHEMBL535 |
