DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
ARALLAALL
Uniprot ID:
O75629
Source protein:
Protein CREG1
Source gene:
CREG1
Class:
DEG_APCC_DBOX_1
Location:
9:17
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.8087
ASA_SCORE:
46.6111
COIL:
0.0077
CONS_SCORE:
0.3607
DSS_SCORE:
0.0471
HELIX:
0.9904
FCONS_SCORE:
1.2143
RIG_SCORE:
0.8534
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with CREG1 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of ARALLAALL
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
O75629
Protein CREG1
DEG_APCC_DBOX_1
9:17
ARALLAALL
APC,CDC20,FZR1
0.8087
More...