DegronMD

Uniprot ID: O94985

Source protein: Calsyntenin-1

Source gene: CLSTN1

Class: DEG_APCC_DBOX_1

Location: 13:21

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5734

ASA_SCORE: 52.5333

COIL: 0.4772

CONS_SCORE: 0.4002

DSS_SCORE: 0.0365

HELIX: 0.114

FCONS_SCORE: 1.1973

RIG_SCORE: 0.8597

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.V26G	DO34640	PACA	ICGC	ARLLLAGLL	DEG_APCC_DBOX_1	0.1944
p.P7S	ACH-000776	Brain Cancer	CCLE	ARLLLAGLL	DEG_APCC_DBOX_1	0.1667
p.C22R	ACH-000943	Colon/Colorectal Cancer	CCLE	ARLLLAGLL	DEG_APCC_DBOX_1	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O94985	Calsyntenin-1	DEG_APCC_DBOX_1	13:21	ARLLLAGLL	APC,CDC20,FZR1	0.5734	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons