DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
ARPSLLQLA
Uniprot ID:
Q8N6U2
Source protein:
Putative uncharacterized protein encoded by LINC00612
Source gene:
LINC00612
Class:
DEG_APCC_DBOX_1
Location:
174:182
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.6178
ASA_SCORE:
104.2111
COIL:
0.7147
CONS_SCORE:
0
DSS_SCORE:
0.6353
HELIX:
0.2306
FCONS_SCORE:
0
RIG_SCORE:
0.7427
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with LINC00612 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of ARPSLLQLA
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8N6U2
Putative uncharacterized protein encoded by LINC00612
DEG_APCC_DBOX_1
174:182
ARPSLLQLA
APC,CDC20,FZR1
0.6178
More...