DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
ARPSLPPLP
Uniprot ID:
Q5TG53
Source protein:
Putative uncharacterized protein SERTAD4-AS1
Source gene:
SERTAD4-AS1
Class:
DEG_APCC_DBOX_1
Location:
3:11
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.8022
ASA_SCORE:
90.6778
COIL:
0.9712
CONS_SCORE:
0
DSS_SCORE:
0.8322
HELIX:
0.0119
FCONS_SCORE:
0
RIG_SCORE:
0.6033
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SERTAD4-AS1 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of ARPSLPPLP
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q5TG53
Putative uncharacterized protein SERTAD4-AS1
DEG_APCC_DBOX_1
3:11
ARPSLPPLP
APC,CDC20,FZR1
0.8022
More...