DegronMD

Uniprot ID: P11279

Source protein: Lysosome-associated membrane glycoprotein 1

Source gene: LAMP1

Class: DEG_APCC_DBOX_1

Location: 7:15

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.8129

ASA_SCORE: 71.3

COIL: 0.3012

CONS_SCORE: 0.474

DSS_SCORE: 0.0152

HELIX: 0.6662

FCONS_SCORE: 1.1916

RIG_SCORE: 0.9257

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.H24Y	TCGA-AX-A1CE	UCEC	TCGA	ARRPLLLLL	DEG_APCC_DBOX_1	0.0833
p.H24Y	DO42280	UCEC	ICGC	ARRPLLLLL	DEG_APCC_DBOX_1	0.0833
p.G21V	DO229025	LICA	ICGC	ARRPLLLLL	DEG_APCC_DBOX_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P11279	Lysosome-associated membrane glycoprotein 1	DEG_APCC_DBOX_1	7:15	ARRPLLLLL	APC,CDC20,FZR1	0.8129	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons