DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
ARRWLRRVR
Uniprot ID:
Q5XG85
Source protein:
Putative UPF0633 protein LOC554249
Source gene:
-
Class:
DEG_APCC_DBOX_1
Location:
33:41
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.6206
ASA_SCORE:
73.0889
COIL:
0.1399
CONS_SCORE:
1
DSS_SCORE:
0.5443
HELIX:
0.816
FCONS_SCORE:
1.0476
RIG_SCORE:
0.7838
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of ARRWLRRVR
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q5XG85
Putative UPF0633 protein LOC554249
DEG_APCC_DBOX_1
33:41
ARRWLRRVR
APC,CDC20,FZR1
0.6206
More...