DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
DADGYDVPDP
Uniprot ID:
A6NE52
Source protein:
WD repeat-containing protein 97
Source gene:
WDR97
Class:
DEG_COP1_1
Location:
21:30
E3 ligase:
COP1
DEGRON score:
0.7258
ASA_SCORE:
33.38
COIL:
0.694
CONS_SCORE:
0.3409
DSS_SCORE:
0.4031
HELIX:
0.0067
FCONS_SCORE:
1.0186
RIG_SCORE:
0.7671
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with WDR97 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of DADGYDVPDP
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NE52
WD repeat-containing protein 97
DEG_COP1_1
21:30
DADGYDVPDP
COP1
0.7258
More...