DegronMD

Uniprot ID: P00533

Source protein: Epidermal growth factor receptor

Source gene: EGFR

Class: DEG_COP1_1

Location: 1083:1092

E3 ligase: COP1

DEGRON score: 0.9978

ASA_SCORE: 90.14

COIL: 0.803

CONS_SCORE: 0.3338

DSS_SCORE: 0.4942

HELIX: 0.1815

FCONS_SCORE: 1.225

RIG_SCORE: 0.8013

Degron related mutations and impact score

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D1084N	TCGA-A5-A0G1	UCEC	TCGA	DDTFLPVPEY	DEG_COP1_1	0.5821
p.V1097I	TCGA-AD-6964	COAD	TCGA	DDTFLPVPEY	DEG_COP1_1	0.1944
p.V1097I	TCGA-C5-A2M2	CESC	TCGA	DDTFLPVPEY	DEG_COP1_1	0.1944
p.V1097I	DO48984	CESC	ICGC	DDTFLPVPEY	DEG_COP1_1	0.1944
p.V1097I	DO8360	COAD	ICGC	DDTFLPVPEY	DEG_COP1_1	0.1944
p.S1096F	TCGA-D5-6928	COAD	TCGA	DDTFLPVPEY	DEG_COP1_1	0.6667
p.S1096F	DO7776	COAD	ICGC	DDTFLPVPEY	DEG_COP1_1	0.6667
p.N1094S	TCGA-DI-A1BU	UCEC	TCGA	DDTFLPVPEY	DEG_COP1_1	0.2778
p.N1094S	DO42023	UCEC	ICGC	DDTFLPVPEY	DEG_COP1_1	0.2778
p.E1079K	TCGA-DK-A3WW	BLCA	TCGA	DDTFLPVPEY	DEG_COP1_1	0.2222
p.D1087H	DO233726	GACA	ICGC	DDTFLPVPEY	DEG_COP1_1	0.7688
p.E1083D	DO222875	MELA	ICGC	DDTFLPVPEY	DEG_COP1_1	0.6758
p.L1075I	DO232224	PBCA	ICGC	DDTFLPVPEY	DEG_COP1_1	0.1111
p.T1085N	SIDM00329	Hodgkin's Lymphoma	GDSC	DDTFLPVPEY	DEG_COP1_1	0.8166
p.T1085N	L-540	haematopoietic_and_lymphoid_tissue	COSMIC	DDTFLPVPEY	DEG_COP1_1	0.8166
p.A1076T	SIDM00429	B-Lymphoblastic Leukemia	GDSC	DDTFLPVPEY	DEG_COP1_1	0.1389
p.A1076T	NALM-6	haematopoietic_and_lymphoid_tissue	COSMIC	DDTFLPVPEY	DEG_COP1_1	0.1389
p.A1086V	SIDM00429	B-Lymphoblastic Leukemia	GDSC	DDTFLPVPEY	DEG_COP1_1	0.6936
p.A1086V	NALM-6	haematopoietic_and_lymphoid_tissue	COSMIC	DDTFLPVPEY	DEG_COP1_1	0.6936
p.D1082N	NCI-H1568	lung	COSMIC	DDTFLPVPEY	DEG_COP1_1	0.3056
p.S1085G	NCI-H2172	lung	COSMIC	DDTFLPVPEY	DEG_COP1_1	0.6993

Drug responses associated with EGFR mutations

Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
ACH-000996	Endometrial/Uterine Cancer	p.K28T (No)	CCLE	Lapatinib	8
ACH-000996	Endometrial/Uterine Cancer	p.K28T (No)	CCLE	ZD-6474	5.546
ACH-000996	Endometrial/Uterine Cancer	p.K28T (No)	CCLE	Erlotinib	8
ACH-000784	Esophageal Cancer	p.T68fs (No)	CCLE	Lapatinib	8
ACH-000784	Esophageal Cancer	p.T68fs (No)	CCLE	ZD-6474	3.4869
ACH-000784	Esophageal Cancer	p.T68fs (No)	CCLE	Erlotinib	2.7443
ACH-000967	Colon/Colorectal Cancer	p.R165Q (No)	CCLE	Lapatinib	8
ACH-000967	Colon/Colorectal Cancer	p.R165Q (No)	CCLE	ZD-6474	8
ACH-000967	Colon/Colorectal Cancer	p.R165Q (No)	CCLE	Erlotinib	8
ACH-001199	Colon/Colorectal Cancer	p.R165Q (No)	CCLE	Lapatinib	3.8048
ACH-001199	Colon/Colorectal Cancer	p.R165Q (No)	CCLE	ZD-6474	8
ACH-001199	Colon/Colorectal Cancer	p.R165Q (No)	CCLE	Erlotinib	8
ACH-000838	Myeloma	p.K164N (No)	CCLE	Lapatinib	0.2564
ACH-000838	Myeloma	p.K164N (No)	CCLE	ZD-6474	3.8644
ACH-000838	Myeloma	p.K164N (No)	CCLE	Erlotinib	8
ACH-000978	Endometrial/Uterine Cancer	p.N234D (No)	CCLE	Lapatinib	8
ACH-000978	Endometrial/Uterine Cancer	p.N234D (No)	CCLE	ZD-6474	8
ACH-000978	Endometrial/Uterine Cancer	p.N234D (No)	CCLE	Erlotinib	8
ACH-000953	Leukemia	p.C251Y (No)	CCLE	Lapatinib	8
ACH-000953	Leukemia	p.C251Y (No)	CCLE	ZD-6474	8
ACH-000953	Leukemia	p.C251Y (No)	CCLE	Erlotinib	8
ACH-000067	Brain Cancer	p.A289D (No)	CCLE	Lapatinib	8
ACH-000067	Brain Cancer	p.A289D (No)	CCLE	ZD-6474	8
ACH-000067	Brain Cancer	p.A289D (No)	CCLE	Erlotinib	8
ACH-000965	Endometrial/Uterine Cancer	p.A244V (No)	CCLE	Lapatinib	3.013
ACH-000965	Endometrial/Uterine Cancer	p.A244V (No)	CCLE	ZD-6474	3.7398
ACH-000965	Endometrial/Uterine Cancer	p.A244V (No)	CCLE	Erlotinib	3.0603
ACH-000984	Endometrial/Uterine Cancer	p.A244V (No)	CCLE	Lapatinib	8
ACH-000984	Endometrial/Uterine Cancer	p.A244V (No)	CCLE	ZD-6474	8
ACH-000984	Endometrial/Uterine Cancer	p.A244V (No)	CCLE	Erlotinib	8
ACH-000445	Brain Cancer	p.V247L (No)	CCLE	Lapatinib	8
ACH-000445	Brain Cancer	p.V247L (No)	CCLE	ZD-6474	8
ACH-000445	Brain Cancer	p.V247L (No)	CCLE	Erlotinib	8
ACH-000805	Skin Cancer	p.S261L (No)	CCLE	Lapatinib	8
ACH-000805	Skin Cancer	p.S261L (No)	CCLE	ZD-6474	8
ACH-000805	Skin Cancer	p.S261L (No)	CCLE	Erlotinib	8
ACH-000248	Breast Cancer	p.R309G (No)	CCLE	Lapatinib	0.1832
ACH-000248	Breast Cancer	p.R309G (No)	CCLE	ZD-6474	8
ACH-000248	Breast Cancer	p.R309G (No)	CCLE	Erlotinib	8
ACH-000264	Lung Cancer	p.R309G (No)	CCLE	Lapatinib	8
ACH-000264	Lung Cancer	p.R309G (No)	CCLE	ZD-6474	8
ACH-000264	Lung Cancer	p.R309G (No)	CCLE	Erlotinib	7.808
ACH-000367	Lung Cancer	p.R309G (No)	CCLE	Lapatinib	8
ACH-000367	Lung Cancer	p.R309G (No)	CCLE	ZD-6474	8
ACH-000367	Lung Cancer	p.R309G (No)	CCLE	Erlotinib	8
ACH-000665	Lung Cancer	p.R309G (No)	CCLE	Lapatinib	1.4764
ACH-000665	Lung Cancer	p.R309G (No)	CCLE	ZD-6474	1.4295
ACH-000665	Lung Cancer	p.R309G (No)	CCLE	Erlotinib	0.9652
ACH-000678	Gastric Cancer	p.R309G (No)	CCLE	Lapatinib	8
ACH-000678	Gastric Cancer	p.R309G (No)	CCLE	ZD-6474	8
ACH-000678	Gastric Cancer	p.R309G (No)	CCLE	Erlotinib	8
ACH-000888	Lung Cancer	p.C311F (No)	CCLE	Lapatinib	8
ACH-000888	Lung Cancer	p.C311F (No)	CCLE	ZD-6474	1.8437
ACH-000888	Lung Cancer	p.C311F (No)	CCLE	Erlotinib	8
ACH-000963	Colon/Colorectal Cancer	p.Q408R (No)	CCLE	Lapatinib	0.2402
ACH-000963	Colon/Colorectal Cancer	p.Q408R (No)	CCLE	ZD-6474	0.7633
ACH-000963	Colon/Colorectal Cancer	p.Q408R (No)	CCLE	Erlotinib	0.6847
ACH-000995	Leukemia	p.R406C (No)	CCLE	Lapatinib	6.7703
ACH-000995	Leukemia	p.R406C (No)	CCLE	ZD-6474	2.3316
ACH-000995	Leukemia	p.R406C (No)	CCLE	Erlotinib	6.0906
ACH-000985	Colon/Colorectal Cancer	p.Q486E (No)	CCLE	Lapatinib	8
ACH-000985	Colon/Colorectal Cancer	p.Q486E (No)	CCLE	ZD-6474	8
ACH-000985	Colon/Colorectal Cancer	p.Q486E (No)	CCLE	Erlotinib	8
ACH-000994	Endometrial/Uterine Cancer	p.R486* (No)	CCLE	Lapatinib	8
ACH-000994	Endometrial/Uterine Cancer	p.R486* (No)	CCLE	ZD-6474	8
ACH-000994	Endometrial/Uterine Cancer	p.R486* (No)	CCLE	Erlotinib	8
ACH-000479	Brain Cancer	p.G598V (No)	CCLE	Lapatinib	8
ACH-000479	Brain Cancer	p.G598V (No)	CCLE	ZD-6474	8
ACH-000479	Brain Cancer	p.G598V (No)	CCLE	Erlotinib	8
ACH-000965	Endometrial/Uterine Cancer	p.G614S (No)	CCLE	Lapatinib	3.013
ACH-000965	Endometrial/Uterine Cancer	p.G614S (No)	CCLE	ZD-6474	3.7398
ACH-000965	Endometrial/Uterine Cancer	p.G614S (No)	CCLE	Erlotinib	3.0603
ACH-000790	Lung Cancer	p.Q701R (No)	CCLE	Lapatinib	8
ACH-000790	Lung Cancer	p.Q701R (No)	CCLE	ZD-6474	8
ACH-000790	Lung Cancer	p.Q701R (No)	CCLE	Erlotinib	8
ACH-000824	Esophageal Cancer	p.A702D (No)	CCLE	Lapatinib	8
ACH-000824	Esophageal Cancer	p.A702D (No)	CCLE	ZD-6474	8
ACH-000824	Esophageal Cancer	p.A702D (No)	CCLE	Erlotinib	8
ACH-000958	Colon/Colorectal Cancer	p.G719S (No)	CCLE	Lapatinib	8
ACH-000958	Colon/Colorectal Cancer	p.G719S (No)	CCLE	ZD-6474	8
ACH-000958	Colon/Colorectal Cancer	p.G719S (No)	CCLE	Erlotinib	1.2151
ACH-000985	Colon/Colorectal Cancer	p.E734* (No)	CCLE	Lapatinib	8
ACH-000985	Colon/Colorectal Cancer	p.E734* (No)	CCLE	ZD-6474	8
ACH-000985	Colon/Colorectal Cancer	p.E734* (No)	CCLE	Erlotinib	8
ACH-000150	Lung Cancer	p.E746fs (No)	CCLE	Lapatinib	1.2399
ACH-000150	Lung Cancer	p.E746fs (No)	CCLE	ZD-6474	0.1947
ACH-000150	Lung Cancer	p.E746fs (No)	CCLE	Erlotinib	0.2808
ACH-000030	Lung Cancer	p.ELREA701del (No)	CCLE	Lapatinib	2.1497
ACH-000030	Lung Cancer	p.ELREA701del (No)	CCLE	ZD-6474	0.226
ACH-000030	Lung Cancer	p.ELREA701del (No)	CCLE	Erlotinib	0.0646
ACH-000035	Lung Cancer	p.ELREA701del (No)	CCLE	Lapatinib	5.1524
ACH-000035	Lung Cancer	p.ELREA701del (No)	CCLE	ZD-6474	0.9891
ACH-000035	Lung Cancer	p.ELREA701del (No)	CCLE	Erlotinib	8
ACH-000066	Lung Cancer	p.ELR701del (No)	CCLE	Lapatinib	1.8549
ACH-000066	Lung Cancer	p.ELR701del (No)	CCLE	ZD-6474	0.4391
ACH-000066	Lung Cancer	p.ELR701del (No)	CCLE	Erlotinib	0.1243
ACH-000012	Lung Cancer	p.ELREA701del (No)	CCLE	Lapatinib	0.3721
ACH-000012	Lung Cancer	p.ELREA701del (No)	CCLE	ZD-6474	0.3174
ACH-000012	Lung Cancer	p.ELREA701del (No)	CCLE	Erlotinib	0.0389
ACH-000150	Lung Cancer	p.LREATS747fs (No)	CCLE	Lapatinib	1.2399
ACH-000150	Lung Cancer	p.LREATS747fs (No)	CCLE	ZD-6474	0.1947
ACH-000150	Lung Cancer	p.LREATS747fs (No)	CCLE	Erlotinib	0.2808
ACH-000176	Lung Cancer	p.747_753LREATSP>S (No)	CCLE	Lapatinib	8
ACH-000176	Lung Cancer	p.747_753LREATSP>S (No)	CCLE	ZD-6474	8
ACH-000176	Lung Cancer	p.747_753LREATSP>S (No)	CCLE	Erlotinib	8
ACH-000176	Lung Cancer	p.A755D (No)	CCLE	Lapatinib	8
ACH-000176	Lung Cancer	p.A755D (No)	CCLE	ZD-6474	8
ACH-000176	Lung Cancer	p.A755D (No)	CCLE	Erlotinib	8
ACH-000899	Skin Cancer	p.E713K (No)	CCLE	Lapatinib	8
ACH-000899	Skin Cancer	p.E713K (No)	CCLE	ZD-6474	8
ACH-000899	Skin Cancer	p.E713K (No)	CCLE	Erlotinib	8
ACH-000865	Esophageal Cancer	p.S768I (No)	CCLE	Lapatinib	2.5745
ACH-000865	Esophageal Cancer	p.S768I (No)	CCLE	ZD-6474	2.1569
ACH-000865	Esophageal Cancer	p.S768I (No)	CCLE	Erlotinib	1.401
ACH-000587	Lung Cancer	p.T790M (No)	CCLE	Lapatinib	8
ACH-000587	Lung Cancer	p.T790M (No)	CCLE	ZD-6474	8
ACH-000587	Lung Cancer	p.T790M (No)	CCLE	Erlotinib	8
ACH-000109	Lung Cancer	p.L858R (No)	CCLE	Lapatinib	0.3338
ACH-000109	Lung Cancer	p.L858R (No)	CCLE	ZD-6474	0.1016
ACH-000109	Lung Cancer	p.L858R (No)	CCLE	Erlotinib	0.0752
ACH-000587	Lung Cancer	p.L858R (No)	CCLE	Lapatinib	8
ACH-000587	Lung Cancer	p.L858R (No)	CCLE	ZD-6474	8
ACH-000587	Lung Cancer	p.L858R (No)	CCLE	Erlotinib	8
ACH-000924	Lung Cancer	p.L858R (No)	CCLE	Lapatinib	8
ACH-000924	Lung Cancer	p.L858R (No)	CCLE	ZD-6474	8
ACH-000924	Lung Cancer	p.L858R (No)	CCLE	Erlotinib	8
ACH-000941	Endometrial/Uterine Cancer	p.A819V (No)	CCLE	Lapatinib	8
ACH-000941	Endometrial/Uterine Cancer	p.A819V (No)	CCLE	ZD-6474	0.4985
ACH-000941	Endometrial/Uterine Cancer	p.A819V (No)	CCLE	Erlotinib	8
ACH-000985	Colon/Colorectal Cancer	p.T940A (No)	CCLE	Lapatinib	8
ACH-000985	Colon/Colorectal Cancer	p.T940A (No)	CCLE	ZD-6474	8
ACH-000985	Colon/Colorectal Cancer	p.T940A (No)	CCLE	Erlotinib	8
ACH-000961	Endometrial/Uterine Cancer	p.R973Q (No)	CCLE	Lapatinib	8
ACH-000961	Endometrial/Uterine Cancer	p.R973Q (No)	CCLE	ZD-6474	2.8005
ACH-000961	Endometrial/Uterine Cancer	p.R973Q (No)	CCLE	Erlotinib	8
ACH-001024	Skin Cancer	p.V1011M (No)	CCLE	Lapatinib	0.676
ACH-001024	Skin Cancer	p.V1011M (No)	CCLE	ZD-6474	4.0328
ACH-001024	Skin Cancer	p.V1011M (No)	CCLE	Erlotinib	3.0498
ACH-000954	Endometrial/Uterine Cancer	p.S980N (No)	CCLE	Lapatinib	8
ACH-000954	Endometrial/Uterine Cancer	p.S980N (No)	CCLE	ZD-6474	8
ACH-000954	Endometrial/Uterine Cancer	p.S980N (No)	CCLE	Erlotinib	8
ACH-000424	Bone Cancer	p.A1003S (No)	CCLE	Lapatinib	8
ACH-000424	Bone Cancer	p.A1003S (No)	CCLE	ZD-6474	8
ACH-000424	Bone Cancer	p.A1003S (No)	CCLE	Erlotinib	8
ACH-000072	Leukemia	p.A1048V (No)	CCLE	Lapatinib	8
ACH-000072	Leukemia	p.A1048V (No)	CCLE	ZD-6474	1.569
ACH-000072	Leukemia	p.A1048V (No)	CCLE	Erlotinib	8
ACH-000356	Gastric Cancer	p.A1048V (No)	CCLE	Lapatinib	8
ACH-000356	Gastric Cancer	p.A1048V (No)	CCLE	ZD-6474	8
ACH-000356	Gastric Cancer	p.A1048V (No)	CCLE	Erlotinib	8
ACH-000963	Colon/Colorectal Cancer	p.Y1069C (No)	CCLE	Lapatinib	0.2402
ACH-000963	Colon/Colorectal Cancer	p.Y1069C (No)	CCLE	ZD-6474	0.7633
ACH-000963	Colon/Colorectal Cancer	p.Y1069C (No)	CCLE	Erlotinib	0.6847
ACH-000869	Lung Cancer	p.D1127N (No)	CCLE	Lapatinib	8
ACH-000869	Lung Cancer	p.D1127N (No)	CCLE	ZD-6474	8
ACH-000869	Lung Cancer	p.D1127N (No)	CCLE	Erlotinib	5.7486
ACH-000924	Lung Cancer	p.S1130G (No)	CCLE	Lapatinib	8
ACH-000924	Lung Cancer	p.S1130G (No)	CCLE	ZD-6474	8
ACH-000924	Lung Cancer	p.S1130G (No)	CCLE	Erlotinib	8
ACH-000205	Pancreatic Cancer	p.W1157C (No)	CCLE	Lapatinib	6.1905
ACH-000205	Pancreatic Cancer	p.W1157C (No)	CCLE	ZD-6474	8
ACH-000205	Pancreatic Cancer	p.W1157C (No)	CCLE	Erlotinib	8
ACH-000666	Lung Cancer	p.Q1159H (No)	CCLE	Lapatinib	7.8607
ACH-000666	Lung Cancer	p.Q1159H (No)	CCLE	ZD-6474	8
ACH-000666	Lung Cancer	p.Q1159H (No)	CCLE	Erlotinib	5.5194
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Erlotinib	15.2829
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Lapatinib	9.9645
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	CUDC-101	0.071
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Pelitinib	2.7356
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Foretinib	0.968
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	CI-1033	35.6605
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	PF-00299804	4.2132
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	AST-1306	4.0874
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Gefitinib	3.1953
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Afatinib	2.576
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Cetuximab	454.1984
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	HG-5-88-01	38.1951
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Afatinib	20.9009
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	AZD8931	6.9416
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Gefitinib	7.6165
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Afatinib	2.6484
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Erlotinib	9.8971
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Sapitinib	67.562
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Lapatinib	3.4949
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	AZD3759	6.71
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Osimertinib	8.0253
SIDM00946	ALL\|T_cell_leukemia	p.Q71* (No)	GDSC	Foretinib	3.7541
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	CUDC-101	0.4897
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Pelitinib	1.703
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Foretinib	0.7773
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	CI-1033	2.5788
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	PF-00299804	2.8728
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	AST-1306	1.8404
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Gefitinib	0.6803
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Afatinib	0.4366
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Cetuximab	261.4414
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Afatinib	7.5142
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	AZD8931	1.9365
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Gefitinib	3.012
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Afatinib	2.1345
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Erlotinib	3.959
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Sapitinib	4.554
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Lapatinib	6.7465
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	AZD3759	2.5578
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Osimertinib	1.2184
SIDM01029	ESCA\|oesophagus	p.L861Q (No)	GDSC	Foretinib	4.3162
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Erlotinib	12.6463
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Lapatinib	5.4865
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	CUDC-101	0.155
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Pelitinib	0.1453
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Foretinib	0.2939
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	CI-1033	3.1853
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	PF-00299804	3.6835
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	AST-1306	1.7412
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Gefitinib	2.4333
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Afatinib	3.1021
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Cetuximab	403.0703
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	HG-5-88-01	43.4064
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Afatinib	25.3127
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	AZD8931	12.2614
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Gefitinib	11.397
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Afatinib	2.8372
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Erlotinib	11.632
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Sapitinib	26.161
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Lapatinib	7.858
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	AZD3759	4.8317
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Osimertinib	1.9545
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.R1068* (No)	GDSC	Foretinib	0.3906
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	CUDC-101	4.6916
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	Pelitinib	14.9509
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	Foretinib	0.7984
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	CI-1033	30.834
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	PF-00299804	18.8439
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	AST-1306	6.8896
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	Gefitinib	6.0982
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	Afatinib	4.1231
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	Cetuximab	192.5381
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	HG-5-88-01	113.2717
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	Afatinib	95.811
SIDM00666	LGG\|glioma	p.A289D (No)	GDSC	AZD8931	6.3363
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Erlotinib	10.6393
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Lapatinib	5.8459
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	CUDC-101	0.1326
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Pelitinib	0.4153
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Foretinib	0.46
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	CI-1033	4.9765
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	PF-00299804	2.5703
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	AST-1306	5.3078
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Gefitinib	2.2944
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Afatinib	2.7142
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Cetuximab	413.9756
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Afatinib	20.0598
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	AZD8931	10.8315
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Gefitinib	21.166
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Afatinib	5.736
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Erlotinib	7.3006
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Sapitinib	47.179
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Lapatinib	20.605
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	AZD3759	14.072
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Osimertinib	4.7322
SIDM00145	ALL\|lymphoblastic_leukemia	p.E513fs*55 (No)	GDSC	Foretinib	0.4244
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Erlotinib	31.1445
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Lapatinib	9.1612
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	CUDC-101	0.1479
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Pelitinib	11.5606
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Foretinib	0.7872
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	CI-1033	71.9491
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	PF-00299804	13.8113
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	AST-1306	16.2295
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Gefitinib	7.4975
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Afatinib	8.688
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Cetuximab	247.4182
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	HG-5-88-01	85.3291
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Afatinib	58.0606
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	AZD8931	3.4106
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Gefitinib	28.601
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Afatinib	9.4823
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Erlotinib	15.754
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Sapitinib	88.73
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Lapatinib	53.336
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	AZD3759	31.831
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Osimertinib	22.984
SIDM00085	GBM\|glioma	p.A289V (No)	GDSC	Foretinib	5.4849
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Erlotinib	16.2877
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Lapatinib	23.118
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	CUDC-101	1.0335
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Pelitinib	5.3028
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Foretinib	0.4609
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	CI-1033	51.0403
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	PF-00299804	15.2578
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	AST-1306	23.595
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Gefitinib	5.0593
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Afatinib	7.0574
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Cetuximab	390.4957
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	HG-5-88-01	148.5934
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Afatinib	15.1807
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	AZD8931	29.2878
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Gefitinib	19.233
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Afatinib	3.4469
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Erlotinib	8.7731
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Sapitinib	233.41
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Lapatinib	13.204
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	AZD3759	9.8428
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Osimertinib	11.344
SIDM00150	COREAD\|large_intestine	p.G573* (No)	GDSC	Foretinib	0.0941
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	CUDC-101	1.7834
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Pelitinib	9.2866
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Foretinib	4.2859
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	CI-1033	9.9381
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	PF-00299804	3.9908
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	AST-1306	4.6547
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Gefitinib	2.5884
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Afatinib	8.8403
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Cetuximab	511.104
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Afatinib	65.2075
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	AZD8931	10.7351
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Gefitinib	67.932
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Afatinib	21.583
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Erlotinib	30.563
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Sapitinib	337.79
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Lapatinib	13.823
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	AZD3759	20.286
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Osimertinib	8.4134
SIDM01024	ESCA\|oesophagus	p.Y69fs*11 (No)	GDSC	Foretinib	22.787
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Erlotinib	9.9122
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Lapatinib	9.6382
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	CUDC-101	11.6663
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Pelitinib	17.2258
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Foretinib	3.2094
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	CI-1033	5.5992
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	PF-00299804	2.1642
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	AST-1306	0.7386
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Gefitinib	1.6438
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Afatinib	4.6047
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Cetuximab	605.94
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Afatinib	72.1516
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	AZD8931	2.784
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Gefitinib	45.592
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Afatinib	8.7495
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Erlotinib	19.878
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Sapitinib	163.66
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Lapatinib	30.056
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	AZD3759	17.693
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Osimertinib	22.908
SIDM01113	UNCLASSIFIED\|soft_tissue_other	p.A653fs*52 (No)	GDSC	Foretinib	6.3112
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Erlotinib	49.6083
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Lapatinib	26.169
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	CUDC-101	1.5083
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Pelitinib	4.6964
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Foretinib	7.5179
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	CI-1033	17.2884
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	PF-00299804	23.4556
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	AST-1306	29.1208
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Gefitinib	4.9764
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Afatinib	0.3868
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Cetuximab	780.0929
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	HG-5-88-01	86.3117
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Afatinib	4.889
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	AZD8931	7.086
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Gefitinib	4.8299
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Afatinib	0.7878
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Erlotinib	5.5926
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Sapitinib	1.9915
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Lapatinib	5.5618
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	AZD3759	9.6645
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Osimertinib	0.5307
SIDM00282	COREAD\|large_intestine	p.G544fs*24 (No)	GDSC	Foretinib	8.0375
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	CUDC-101	2.8856
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Pelitinib	48.7551
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Foretinib	1.9602
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	CI-1033	148.6927
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	PF-00299804	19.7133
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	AST-1306	9.4593
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Gefitinib	1.9277
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Afatinib	9.1696
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Cetuximab	726.4655
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Afatinib	104.2298
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	AZD8931	18.906
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Gefitinib	47.725
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Afatinib	110.08
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Erlotinib	42.715
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Sapitinib	324.88
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Lapatinib	485.6
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	AZD3759	34.837
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Osimertinib	26.03
SIDM00343	GBM\|glioma	p.L62R (No)	GDSC	Foretinib	7.3611
SIDM00895	DLBC\|B_cell_lymphoma	p.R108K (No)	GDSC	Erlotinib	13.1674
SIDM00895	DLBC\|B_cell_lymphoma	p.R108K (No)	GDSC	Lapatinib	9.0247
SIDM00895	DLBC\|B_cell_lymphoma	p.R108K (No)	GDSC	CUDC-101	0.2786
SIDM00895	DLBC\|B_cell_lymphoma	p.R108K (No)	GDSC	Pelitinib	1.3857
SIDM00895	DLBC\|B_cell_lymphoma	p.R108K (No)	GDSC	Foretinib	0.9474
SIDM00895	DLBC\|B_cell_lymphoma	p.R108K (No)	GDSC	CI-1033	34.2956
SIDM00895	DLBC\|B_cell_lymphoma	p.R108K (No)	GDSC	PF-00299804	11.2117
SIDM00895	DLBC\|B_cell_lymphoma	p.R108K (No)	GDSC	AST-1306	5.716
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Erlotinib	10.0269
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Lapatinib	17.8522
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	CUDC-101	1.3804
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Pelitinib	0.0604
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Foretinib	2.6401
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	CI-1033	2.1347
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	PF-00299804	1.6263
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	AST-1306	1.1852
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Gefitinib	6.3024
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Afatinib	0.3848
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Cetuximab	69.9293
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	HG-5-88-01	15.572
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Afatinib	2.1157
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	AZD8931	2.622
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Gefitinib	13.448
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Afatinib	0.3772
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Erlotinib	6.094
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Sapitinib	3.5253
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Lapatinib	37.038
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	AZD3759	22.675
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Osimertinib	0.0377
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.T790M (No)	GDSC	Foretinib	4.7301
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Erlotinib	10.0269
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Lapatinib	17.8522
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	CUDC-101	1.3804
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Pelitinib	0.0604
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Foretinib	2.6401
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	CI-1033	2.1347
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	PF-00299804	1.6263
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	AST-1306	1.1852
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Gefitinib	6.3024
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Afatinib	0.3848
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Cetuximab	69.9293
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	HG-5-88-01	15.572
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Afatinib	2.1157
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	AZD8931	2.622
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Gefitinib	13.448
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Afatinib	0.3772
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Erlotinib	6.094
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Sapitinib	3.5253
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Lapatinib	37.038
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	AZD3759	22.675
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Osimertinib	0.0377
SIDM00759	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Foretinib	4.7301
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	CUDC-101	0.165
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Pelitinib	0.0543
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Foretinib	6.4826
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	CI-1033	0.2929
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	PF-00299804	0.2417
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	AST-1306	0.2463
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Gefitinib	0.0121
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Afatinib	0.0045
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Cetuximab	6.8975
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Afatinib	0.0346
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	AZD8931	0.0531
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Afatinib	0.0182
SIDM00046	LUAD\|lung_NSCLC_adenocarcinoma	p.L858R (No)	GDSC	Sapitinib	0.0978
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	CUDC-101	0.1521
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Pelitinib	0.0106
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Foretinib	0.2734
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	CI-1033	0.2481
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	PF-00299804	0.5468
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	AST-1306	0.4875
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Gefitinib	0.2197
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Afatinib	0.0569
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Cetuximab	19.5308
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	HG-5-88-01	100.8627
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Afatinib	0.1128
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	AZD8931	0.0444
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Gefitinib	0.5321
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Afatinib	0.4005
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Erlotinib	0.8434
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Sapitinib	0.5591
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Lapatinib	1.8644
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	AZD3759	1.2177
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Osimertinib	0.491
SIDM01027	ESCA\|oesophagus	p.S768I (No)	GDSC	Foretinib	2.818
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	CUDC-101	0.2537
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Pelitinib	21.9575
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Foretinib	0.7021
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	CI-1033	37.7483
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	PF-00299804	47.4842
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	AST-1306	9.4265
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Gefitinib	0.3705
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Afatinib	0.264
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Cetuximab	55.534
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	HG-5-88-01	2.7374
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Afatinib	6.5809
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	AZD8931	0.5404
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Gefitinib	1.2997
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Afatinib	1.1428
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Erlotinib	0.9932
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Sapitinib	3.012
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Lapatinib	0.8443
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	AZD3759	0.3465
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Osimertinib	0.2861
SIDM00837	COREAD\|large_intestine	p.G719S (No)	GDSC	Foretinib	0.3001
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	CUDC-101	0.8252
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Pelitinib	6.6856
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Foretinib	3.1924
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	CI-1033	8.4237
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	PF-00299804	22.8686
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	AST-1306	16.8593
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Gefitinib	8.0066
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Afatinib	4.2805
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Cetuximab	951.4784
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Afatinib	41.8728
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	AZD8931	26.5594
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Gefitinib	34.069
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Afatinib	18.579
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Erlotinib	42.986
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Sapitinib	252.4
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Lapatinib	345.09
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	AZD3759	10.984
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Osimertinib	19.155
SIDM00284	SKCM\|melanoma	p.S306L (No)	GDSC	Foretinib	3.7086
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	CUDC-101	110.9178
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	Pelitinib	33.3562
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	Foretinib	2.9466
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	CI-1033	625.7219
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	PF-00299804	634.8413
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	AST-1306	607.8213
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	Gefitinib	8.7071
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	Afatinib	13.8408
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	Cetuximab	1447.4143
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	Afatinib	173.6269
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.S1130G (No)	GDSC	AZD8931	25.4631
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	CUDC-101	46.5369
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Pelitinib	29.8809
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Foretinib	4.4547
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	CI-1033	69.0899
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	PF-00299804	9.5432
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	AST-1306	6.3128
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Gefitinib	1.049
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Afatinib	1.1883
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	HG-5-88-01	19.6396
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Afatinib	8.1424
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	AZD8931	0.9575
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Gefitinib	183.22
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Afatinib	7.0168
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Erlotinib	24.638
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Sapitinib	23.948
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Lapatinib	165.66
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	AZD3759	34.835
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Osimertinib	39.741
SIDM00720	MESO\|mesothelioma	p.S703F (No)	GDSC	Foretinib	4.3087
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Erlotinib	13.9393
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Lapatinib	17.1911
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	CUDC-101	0.6931
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Pelitinib	0.292
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Foretinib	0.0593
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	CI-1033	1.8347
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	PF-00299804	4.3972
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	AST-1306	3.5231
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Gefitinib	0.818
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Afatinib	2.6175
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Cetuximab	737.4594
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Afatinib	34.2413
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	AZD8931	11.2389
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Gefitinib	24.096
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Afatinib	4.7506
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Erlotinib	4.8703
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Sapitinib	17.752
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Lapatinib	27.303
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	AZD3759	9.8272
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Osimertinib	2.8878
SIDM00526	LCML\|chronic_myeloid_leukaemia	p.A1048V (No)	GDSC	Foretinib	0.1324
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Erlotinib	13.6119
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Lapatinib	16.1771
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	CUDC-101	0.3221
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Pelitinib	5.9732
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Foretinib	0.1434
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	CI-1033	138.0133
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	PF-00299804	8.5031
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	AST-1306	172.2914
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Gefitinib	2.4018
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Afatinib	2.477
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Cetuximab	567.0826
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Afatinib	86.1827
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	AZD8931	4.3674
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Gefitinib	16.038
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Afatinib	0.8189
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Erlotinib	13.564
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Sapitinib	4.0777
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Lapatinib	3.8321
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	AZD3759	4.6219
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Osimertinib	0.7965
SIDM00412	UNCLASSIFIED\|lymphoid_neoplasm_other	p.T168M (No)	GDSC	Foretinib	0.7641
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	CUDC-101	0.1033
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Pelitinib	0.2341
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Foretinib	0.3922
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	CI-1033	0.3935
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	PF-00299804	0.1643
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	AST-1306	0.2247
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Gefitinib	0.1736
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Afatinib	0.0227
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Cetuximab	550.2617
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Afatinib	0.13
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	AZD8931	0.127
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Gefitinib	7.9475
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Afatinib	2.0384
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Erlotinib	6.1317
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Sapitinib	3.0639
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Lapatinib	3.7421
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	AZD3759	7.7395
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Osimertinib	0.5773
SIDM01228	SKCM\|melanoma	p.V1011M (No)	GDSC	Foretinib	3.3402
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	CUDC-101	1.7834
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Pelitinib	9.2866
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Foretinib	4.2859
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	CI-1033	9.9381
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	PF-00299804	3.9908
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	AST-1306	4.6547
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Gefitinib	2.5884
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Afatinib	8.8403
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Cetuximab	511.104
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Afatinib	65.2075
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	AZD8931	10.7351
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Gefitinib	67.932
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Afatinib	21.583
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Erlotinib	30.563
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Sapitinib	337.79
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Lapatinib	13.823
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	AZD3759	20.286
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Osimertinib	8.4134
SIDM01024	ESCA\|oesophagus	p.P672R (No)	GDSC	Foretinib	22.787
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Erlotinib	3.4399
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Lapatinib	4.5311
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	CUDC-101	0.879
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Pelitinib	0.1791
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Foretinib	1.592
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	CI-1033	5.5469
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	PF-00299804	4.0074
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	AST-1306	2.3102
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Gefitinib	5.3672
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Afatinib	2.1316
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Cetuximab	227.6533
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	HG-5-88-01	10.5801
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Afatinib	10.4557
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	AZD8931	3.2953
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Gefitinib	9.7727
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Afatinib	3.154
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Erlotinib	2.5053
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Sapitinib	6.5793
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Lapatinib	9.3912
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	AZD3759	6.1298
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Osimertinib	1.7312
SIDM00778	COREAD\|large_intestine	p.E282K (No)	GDSC	Foretinib	4.6094
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	CUDC-101	0.1658
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Pelitinib	0.132
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Foretinib	0.4204
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	CI-1033	5.4471
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	PF-00299804	2.5229
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	AST-1306	2.1192
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Gefitinib	0.1799
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Afatinib	0.0248
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Cetuximab	245.569
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	HG-5-88-01	6.6458
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Afatinib	0.072
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	AZD8931	0.0691
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Gefitinib	0.1997
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Afatinib	0.0568
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Erlotinib	0.115
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Sapitinib	0.0505
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Lapatinib	2.3026
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	AZD3759	0.1047
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Osimertinib	0.0428
SIDM00237	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Foretinib	2.7667
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	CUDC-101	2.6955
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Pelitinib	73.4105
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Foretinib	51.0935
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	CI-1033	11.7349
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	PF-00299804	20.7714
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	AST-1306	11.4067
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Gefitinib	2.7636
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Afatinib	2.8628
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Cetuximab	365.1941
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	HG-5-88-01	33.4761
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Afatinib	12.1849
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	AZD8931	9.1243
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Gefitinib	12.612
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Afatinib	11.882
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Erlotinib	13.707
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Sapitinib	123.74
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Lapatinib	9.9406
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	AZD3759	12.458
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Osimertinib	14.683
SIDM00213	THCA\|thyroid	p.A1118T (No)	GDSC	Foretinib	4.987
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	CUDC-101	0.3577
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Pelitinib	0.3898
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Foretinib	0.1349
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	CI-1033	7.135
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	PF-00299804	5.1106
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	AST-1306	5.2058
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Gefitinib	3.1033
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Afatinib	2.9763
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Cetuximab	651.8138
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	HG-5-88-01	100.8094
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Afatinib	75.0108
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	AZD8931	2.0724
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Gefitinib	6.385
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Afatinib	0.8859
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Erlotinib	9.235
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Sapitinib	12.214
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Lapatinib	4.8725
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	AZD3759	25.708
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Osimertinib	1.4169
SIDM00210	UNCLASSIFIED\|ovary	p.S703F (No)	GDSC	Foretinib	0.491
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Erlotinib	18.2223
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Lapatinib	18.6534
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	CUDC-101	0.5127
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Pelitinib	1.6732
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Foretinib	2.6887
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	CI-1033	9.077
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	PF-00299804	5.3432
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	AST-1306	4.4026
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Gefitinib	0.6881
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Afatinib	1.2576
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Cetuximab	804.2748
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Afatinib	73.3273
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	AZD8931	43.1266
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Gefitinib	18.48
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Afatinib	4.0132
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Erlotinib	6.5024
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Sapitinib	57.367
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Lapatinib	11.84
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	AZD3759	12.26
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Osimertinib	3.1153
SIDM00087	MM\|myeloma	p.T751I (No)	GDSC	Foretinib	3.6643
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	CUDC-101	0.023
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Pelitinib	0.3317
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Foretinib	0.3157
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	CI-1033	2.6201
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	PF-00299804	2.4
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	AST-1306	2.8564
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Gefitinib	0.4509
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Afatinib	0.4953
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Cetuximab	530.9947
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Afatinib	21.6256
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	AZD8931	29.1326
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Gefitinib	19.179
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Afatinib	2.1895
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Erlotinib	13.895
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Sapitinib	26.392
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Lapatinib	5.322
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	AZD3759	12.895
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Osimertinib	2.6598
SIDM00433	ALL\|lymphoblastic_T_cell_leukaemia	p.R220H (No)	GDSC	Foretinib	0.7013
SIDM00449	UNCLASSIFIED\|B_cell_leukemia	p.R677C (No)	GDSC	CI-1033	3.2811
SIDM00449	UNCLASSIFIED\|B_cell_leukemia	p.R677C (No)	GDSC	PF-00299804	2.7868
SIDM00449	UNCLASSIFIED\|B_cell_leukemia	p.R677C (No)	GDSC	AST-1306	2.4304
SIDM00449	UNCLASSIFIED\|B_cell_leukemia	p.R677C (No)	GDSC	Gefitinib	1.7638
SIDM00449	UNCLASSIFIED\|B_cell_leukemia	p.R677C (No)	GDSC	Afatinib	1.5736
SIDM00449	UNCLASSIFIED\|B_cell_leukemia	p.R677C (No)	GDSC	Cetuximab	371.9632
SIDM00449	UNCLASSIFIED\|B_cell_leukemia	p.R677C (No)	GDSC	Afatinib	29.8682
SIDM00449	UNCLASSIFIED\|B_cell_leukemia	p.R677C (No)	GDSC	AZD8931	4.2533
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	Erlotinib	19.3672
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	Lapatinib	8.8524
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	CUDC-101	0.7823
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	Pelitinib	3.7878
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	Foretinib	1.3272
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	CI-1033	4.0702
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	PF-00299804	23.2795
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	AST-1306	12.0566
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	Gefitinib	7.5353
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	Afatinib	7.1355
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	Cetuximab	732.7635
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	Afatinib	29.9779
SIDM00179	SKCM\|melanoma	p.F961L (No)	GDSC	AZD8931	7.5513
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Erlotinib	15.278
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Lapatinib	14.7118
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	CUDC-101	0.0671
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Pelitinib	0.4033
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Foretinib	0.2992
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	CI-1033	2.3695
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	PF-00299804	1.8062
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	AST-1306	3.4086
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Gefitinib	0.6551
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Afatinib	1.7433
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Cetuximab	675.9371
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Afatinib	55.0811
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	AZD8931	21.9815
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Gefitinib	12.567
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Afatinib	1.9481
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Erlotinib	5.8016
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Sapitinib	25.973
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Lapatinib	3.6472
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	AZD3759	6.2967
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Osimertinib	3.7181
SIDM00121	ALL\|lymphoblastic_leukemia	p.A1118T (No)	GDSC	Foretinib	0.2245
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Erlotinib	12.6463
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Lapatinib	5.4865
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	CUDC-101	0.155
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Pelitinib	0.1453
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Foretinib	0.2939
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	CI-1033	3.1853
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	PF-00299804	3.6835
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	AST-1306	1.7412
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Gefitinib	2.4333
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Afatinib	3.1021
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Cetuximab	403.0703
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	HG-5-88-01	43.4064
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Afatinib	25.3127
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	AZD8931	12.2614
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Gefitinib	11.397
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Afatinib	2.8372
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Erlotinib	11.632
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Sapitinib	26.161
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Lapatinib	7.858
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	AZD3759	4.8317
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Osimertinib	1.9545
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1076T (Yes)	GDSC	Foretinib	0.3906
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Erlotinib	12.6463
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Lapatinib	5.4865
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	CUDC-101	0.155
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Pelitinib	0.1453
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Foretinib	0.2939
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	CI-1033	3.1853
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	PF-00299804	3.6835
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	AST-1306	1.7412
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Gefitinib	2.4333
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Afatinib	3.1021
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Cetuximab	403.0703
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	HG-5-88-01	43.4064
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Afatinib	25.3127
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	AZD8931	12.2614
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Gefitinib	11.397
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Afatinib	2.8372
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Erlotinib	11.632
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Sapitinib	26.161
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Lapatinib	7.858
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	AZD3759	4.8317
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Osimertinib	1.9545
SIDM00429	UNCLASSIFIED\|B_cell_leukemia	p.A1086V (Yes)	GDSC	Foretinib	0.3906
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	CUDC-101	1.0625
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	Pelitinib	45.9354
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	Foretinib	1.4262
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	CI-1033	6.6081
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	PF-00299804	1.2297
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	AST-1306	0.628
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	Gefitinib	1.4228
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	Afatinib	4.2032
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	Cetuximab	400.1658
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	HG-5-88-01	38.1201
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	Afatinib	33.0753
SIDM00081	SKCM\|melanoma	p.P753S (No)	GDSC	AZD8931	17.9175
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Erlotinib	34.0997
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Lapatinib	30.2524
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	CUDC-101	0.1712
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Pelitinib	2.7825
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Foretinib	5.9943
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	CI-1033	13.1536
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	PF-00299804	13.0157
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	AST-1306	27.4993
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Gefitinib	8.5648
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Afatinib	3.8954
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Cetuximab	392.1228
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	HG-5-88-01	138.8615
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Afatinib	103.9555
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	AZD8931	3.3096
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Gefitinib	68.791
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Afatinib	2.8002
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Erlotinib	61.659
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Sapitinib	122.67
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Lapatinib	9.3907
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	AZD3759	11.577
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Osimertinib	1.6039
SIDM00683	PRAD\|prostate	p.P1071L (No)	GDSC	Foretinib	4.473
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	CUDC-101	0.3739
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Pelitinib	1.305
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Foretinib	1.1352
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	CI-1033	1.8566
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	PF-00299804	0.1887
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	AST-1306	0.4272
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Gefitinib	0.1468
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Afatinib	0.0374
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Cetuximab	29.0225
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Afatinib	0.25
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	AZD8931	0.0427
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Gefitinib	1.2782
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Afatinib	0.1438
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Erlotinib	2.1784
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Sapitinib	0.7603
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Lapatinib	3.0848
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	AZD3759	1.5807
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Osimertinib	0.3905
SIDM00350	HNSC\|head_and_neck	p.G312E (No)	GDSC	Foretinib	3.0063
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	CUDC-101	2.4266
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Pelitinib	15.1761
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Foretinib	0.8891
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	CI-1033	17.1316
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	PF-00299804	16.9735
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	AST-1306	16.8224
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Gefitinib	2.8499
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Afatinib	4.6616
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Cetuximab	462.5691
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Afatinib	81.3327
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	AZD8931	78.4382
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Gefitinib	11.057
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Afatinib	33.267
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Erlotinib	17.15
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Sapitinib	74.457
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Lapatinib	13.652
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	AZD3759	14.674
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Osimertinib	12.771
SIDM00846	CESC\|cervix	p.I646L (No)	GDSC	Foretinib	1.4891
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Erlotinib	18.5134
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Lapatinib	14.2693
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	CUDC-101	0.5424
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Pelitinib	2.0047
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Foretinib	1.2032
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	CI-1033	52.3177
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	PF-00299804	9.1914
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	AST-1306	9.9412
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Gefitinib	1.389
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Afatinib	3.6589
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Cetuximab	275.8516
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	HG-5-88-01	29.1459
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Afatinib	91.2829
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	AZD8931	3.6638
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Gefitinib	10.992
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Afatinib	3.0567
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Erlotinib	12.856
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Sapitinib	46.192
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Lapatinib	7.9034
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	AZD3759	6.0859
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Osimertinib	4.8577
SIDM01078	SCLC\|lung_small_cell_carcinoma	p.Q701R (No)	GDSC	Foretinib	3.3236
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Erlotinib	12.764
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Lapatinib	17.3731
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	CUDC-101	0.0617
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Pelitinib	0.2172
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Foretinib	0.1908
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	CI-1033	3.0971
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	PF-00299804	1.6503
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	AST-1306	3.0199
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Gefitinib	1.0078
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Afatinib	0.8013
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Cetuximab	449.0652
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Afatinib	67.6844
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	AZD8931	5.838
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Gefitinib	5.8206
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Afatinib	1.9614
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Erlotinib	4.5172
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Sapitinib	27.328
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Lapatinib	4.3193
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	AZD3759	6.2413
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Osimertinib	8.2625
SIDM01007	ALL\|lymphoblastic_leukemia	p.L76P (No)	GDSC	Foretinib	0.4275
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	CUDC-101	0.32
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Pelitinib	2.8248
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Foretinib	3.9915
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	CI-1033	11.2025
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	PF-00299804	2.8488
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	AST-1306	4.3635
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Gefitinib	1.8742
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Afatinib	1.075
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Cetuximab	894.7855
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	HG-5-88-01	55.7984
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Afatinib	13.7266
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	AZD8931	4.3087
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Gefitinib	80.875
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Afatinib	6.9043
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Erlotinib	39.629
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Sapitinib	26.071
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Lapatinib	25.896
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	AZD3759	30.844
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Osimertinib	6.0547
SIDM00781	COREAD\|large_intestine	p.R165Q (No)	GDSC	Foretinib	10.275
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	CUDC-101	0.779
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Pelitinib	15.1008
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Foretinib	6.0715
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	CI-1033	11.0384
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	PF-00299804	7.2031
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	AST-1306	4.3039
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Gefitinib	6.0578
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Afatinib	4.8192
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Cetuximab	396.6154
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Afatinib	54.4963
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	AZD8931	10.7204
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Gefitinib	34.82
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Afatinib	5.3557
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Erlotinib	19.925
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Sapitinib	50.452
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Lapatinib	10.551
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	AZD3759	14.287
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Osimertinib	8.7353
SIDM00146	BRCA\|breast	p.L469W (No)	GDSC	Foretinib	4.9232
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	CUDC-101	6.144
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Pelitinib	87.6299
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Foretinib	5.5521
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	CI-1033	12.0733
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	PF-00299804	19.777
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	AST-1306	6.0158
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Gefitinib	2.6541
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Afatinib	3.297
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Cetuximab	836.6142
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Afatinib	46.967
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	AZD8931	6.8992
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Gefitinib	98.792
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Afatinib	47.75
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Erlotinib	62.576
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Sapitinib	122.82
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Lapatinib	654.34
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	AZD3759	116.11
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Osimertinib	52.391
SIDM00755	LUAD\|lung_NSCLC_adenocarcinoma	p.C311F (No)	GDSC	Foretinib	27.967
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	CUDC-101	0.4087
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Pelitinib	58.351
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Foretinib	2.9816
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	CI-1033	10.7098
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	PF-00299804	8.6768
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	AST-1306	5.2759
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Gefitinib	2.6763
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Afatinib	6.6097
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Cetuximab	625.189
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	HG-5-88-01	28.0806
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Afatinib	114.1787
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	AZD8931	12.1664
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Gefitinib	104.54
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Afatinib	13.681
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Erlotinib	10.929
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Sapitinib	716.62
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Lapatinib	56.985
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	AZD3759	37.598
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Osimertinib	7.6863
SIDM00321	UNCLASSIFIED\|ovary	p.A202_Q208delinsE (No)	GDSC	Foretinib	19.882
SIDM00126	SKCM\|melanoma	p.K1052E (No)	GDSC	CUDC-101	1.4522
SIDM00126	SKCM\|melanoma	p.K1052E (No)	GDSC	Pelitinib	60.6963
SIDM00126	SKCM\|melanoma	p.K1052E (No)	GDSC	Foretinib	2.546
SIDM00126	SKCM\|melanoma	p.K1052E (No)	GDSC	Gefitinib	14.5428
SIDM00126	SKCM\|melanoma	p.K1052E (No)	GDSC	Afatinib	14.5428
SIDM00126	SKCM\|melanoma	p.K1052E (No)	GDSC	Cetuximab	135.6404
SIDM00126	SKCM\|melanoma	p.K1052E (No)	GDSC	HG-5-88-01	33.0065
SIDM00126	SKCM\|melanoma	p.K1052E (No)	GDSC	Afatinib	236.3493
SIDM00126	SKCM\|melanoma	p.K1052E (No)	GDSC	AZD8931	5.006
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	CUDC-101	17.3069
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	Pelitinib	14.4643
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	Foretinib	18.4258
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	CI-1033	5.3833
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	PF-00299804	9.4988
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	AST-1306	5.8617
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	Gefitinib	2.3428
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	Afatinib	1.6957
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	Cetuximab	154.4262
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	Afatinib	65.0449
SIDM00052	ESCA\|oesophagus	p.S703F (No)	GDSC	AZD8931	4.3659
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	CUDC-101	0.6762
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Pelitinib	0.845
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Foretinib	0.6811
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	CI-1033	16.3474
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	PF-00299804	16.5693
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	AST-1306	13.2789
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Gefitinib	1.4972
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Afatinib	1.9549
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Cetuximab	315.9408
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	HG-5-88-01	17.7375
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Afatinib	43.5802
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	AZD8931	0.068
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Gefitinib	50.012
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Afatinib	4.4606
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Erlotinib	7.4472
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Sapitinib	17.668
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Lapatinib	10.691
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	AZD3759	4.8108
SIDM00214	COREAD\|large_intestine	p.V292M (No)	GDSC	Osimertinib	2.7127
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Erlotinib	5.9689
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Lapatinib	4.6105
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	CUDC-101	0.2341
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Pelitinib	19.3081
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Foretinib	0.3304
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	CI-1033	1.8076
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	PF-00299804	0.8176
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	AST-1306	0.4803
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Gefitinib	0.7749
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Afatinib	0.2447
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Cetuximab	369.2205
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	HG-5-88-01	46.7651
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Afatinib	11.7268
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	AZD8931	3.1835
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Gefitinib	9.8954
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Afatinib	5.0618
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Erlotinib	5.9026
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Sapitinib	47.336
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Lapatinib	9.3957
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	AZD3759	13.723
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Osimertinib	4.8831
SIDM01088	UNCLASSIFIED\|endometrium	p.G614S (No)	GDSC	Foretinib	1.992
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	CUDC-101	28.7815
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Pelitinib	216.3869
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Foretinib	3.261
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	CI-1033	600.9063
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	PF-00299804	33.135
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	AST-1306	719.9574
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Gefitinib	4.8419
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Afatinib	6.1103
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Cetuximab	2186.7835
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	HG-5-88-01	263.7907
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Afatinib	282.6991
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	AZD8931	16.257
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Gefitinib	209.82
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Afatinib	184.56
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Erlotinib	188.15
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Sapitinib	51.11
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Lapatinib	195.15
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	AZD3759	59.223
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Osimertinib	34.556
SIDM00484	THCA\|thyroid	p.K327E (No)	GDSC	Foretinib	0.6696
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	CI-1033	7.4296
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	PF-00299804	4.6378
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	AST-1306	5.9937
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Gefitinib	5.5863
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Afatinib	6.4332
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Cetuximab	890.0539
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Afatinib	51.7357
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	AZD8931	39.9118
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Gefitinib	27.754
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Afatinib	1.9009
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Erlotinib	36.454
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Sapitinib	90.508
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Lapatinib	4.3736
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	AZD3759	15.708
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Osimertinib	7.8638
SIDM01133	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S703F (No)	GDSC	Foretinib	0.8389
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	CUDC-101	0.6925
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Pelitinib	76.0131
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Foretinib	2.3885
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	CI-1033	41.8079
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	PF-00299804	12.7935
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	AST-1306	2.5668
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Gefitinib	1.1667
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Afatinib	1.48
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Cetuximab	729.5099
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Afatinib	52.864
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	AZD8931	7.9825
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Gefitinib	56.405
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Afatinib	44.302
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Erlotinib	29.483
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Sapitinib	22.557
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Lapatinib	38.283
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	AZD3759	26.755
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Osimertinib	19.121
SIDM00529	BRCA\|breast	p.S703F (No)	GDSC	Foretinib	3.4666
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	CUDC-101	2.6561
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Pelitinib	1.6613
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Foretinib	2.3061
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	CI-1033	10.4782
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	PF-00299804	12.2386
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	AST-1306	6.2651
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Gefitinib	7.2927
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Afatinib	4.3477
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Cetuximab	246.5942
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	HG-5-88-01	29.2304
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Afatinib	22.0604
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	AZD8931	15.5832
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Gefitinib	23.651
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Afatinib	5.0739
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Erlotinib	10.175
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Sapitinib	34.195
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Lapatinib	165.97
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	AZD3759	19.018
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Osimertinib	2.8441
SIDM00751	LUAD\|lung_NSCLC_adenocarcinoma	p.N1184fs*4 (No)	GDSC	Foretinib	2.2339
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Erlotinib	5.7385
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Lapatinib	18.1706
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	CUDC-101	0.1645
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Pelitinib	0.5946
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Foretinib	1.3948
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	CI-1033	7.0529
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	PF-00299804	3.5027
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	AST-1306	4.1254
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Cetuximab	314.4613
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	HG-5-88-01	71.6708
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Afatinib	70.8821
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	AZD8931	4.6816
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Gefitinib	12.515
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Afatinib	5.7747
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Erlotinib	3.185
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Sapitinib	148.43
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Lapatinib	153.97
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	AZD3759	8.2803
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Osimertinib	5.2618
SIDM00668	UNCLASSIFIED\|Hodgkin_lymphoma	p.R165W (No)	GDSC	Foretinib	4.5444
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Erlotinib	27.0913
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Lapatinib	22.6265
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Pelitinib	2.8377
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Foretinib	1.2719
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	CI-1033	4.384
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	PF-00299804	3.1422
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	AST-1306	4.5006
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Gefitinib	5.1033
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Afatinib	8.7975
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Cetuximab	812.9194
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Afatinib	59.0467
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	AZD8931	13.1016
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Gefitinib	25.278
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Afatinib	3.3484
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Erlotinib	13.447
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Sapitinib	28.531
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Lapatinib	5.3569
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	AZD3759	20.148
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Osimertinib	2.1732
SIDM00793	UNCLASSIFIED\|Burkitt_lymphoma	p.E866D (No)	GDSC	Foretinib	5.5147
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Erlotinib	28.3002
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Lapatinib	2.5691
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	CUDC-101	0.7078
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Pelitinib	23.8593
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Foretinib	1.5647
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	CI-1033	280.1906
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	PF-00299804	26.4909
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	AST-1306	8.0447
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Gefitinib	3.3214
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Afatinib	5.7724
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Cetuximab	499.926
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	HG-5-88-01	24.5691
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Afatinib	69.1014
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	AZD8931	6.5111
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Gefitinib	29.266
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Afatinib	6.1165
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Erlotinib	22.926
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Sapitinib	9.4449
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Lapatinib	24.667
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	AZD3759	6.0848
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Osimertinib	6.7769
SIDM00252	UNCLASSIFIED\|biliary_tract	p.L883F (No)	GDSC	Foretinib	3.1573
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Gefitinib	1.0674
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Afatinib	2.9154
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	AZD8931	9.7092
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Gefitinib	26.242
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Afatinib	8.0653
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Erlotinib	4.1793
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Sapitinib	9.9507
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Lapatinib	27.125
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	AZD3759	3.403
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Osimertinib	1.9721
SIDM00745	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Foretinib	5.8519
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	CUDC-101	0.6841
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Pelitinib	89.1918
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Foretinib	1.0216
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	CI-1033	8.0757
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	PF-00299804	18.0968
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	AST-1306	8.8172
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Gefitinib	18.3234
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Afatinib	18.0713
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Cetuximab	577.2417
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	HG-5-88-01	212.4458
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Afatinib	200.0329
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Gefitinib	73.017
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Afatinib	13.534
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Erlotinib	63.52
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Sapitinib	288.35
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Lapatinib	85.551
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	AZD3759	32.377
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Osimertinib	15.067
SIDM01045	UCEC\|endometrium	p.N234D (No)	GDSC	Foretinib	4.4671
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	Erlotinib	21.8821
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	Lapatinib	11.093
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	CUDC-101	0.7175
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	Pelitinib	55.2398
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	Foretinib	1.7131
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	CI-1033	324.6793
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	PF-00299804	30.7032
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	AST-1306	17.1656
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	Gefitinib	6.7811
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	Afatinib	7.3736
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	Cetuximab	2328.5639
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	Afatinib	236.5406
SIDM01210	LGG\|glioma	p.E140* (No)	GDSC	AZD8931	255.4136
SIDM01265	MM\|myeloma	p.G917R (No)	GDSC	Gefitinib	2.4056
SIDM01265	MM\|myeloma	p.G917R (No)	GDSC	Afatinib	4.2108
SIDM01265	MM\|myeloma	p.G917R (No)	GDSC	Gefitinib	14.912
SIDM01265	MM\|myeloma	p.G917R (No)	GDSC	Afatinib	4.9077
SIDM01265	MM\|myeloma	p.G917R (No)	GDSC	Erlotinib	10.296
SIDM01265	MM\|myeloma	p.G917R (No)	GDSC	Sapitinib	57.963
SIDM01265	MM\|myeloma	p.G917R (No)	GDSC	Lapatinib	75.96
SIDM01265	MM\|myeloma	p.G917R (No)	GDSC	AZD3759	7.42
SIDM01265	MM\|myeloma	p.G917R (No)	GDSC	Osimertinib	2.2504
SIDM01265	MM\|myeloma	p.G917R (No)	GDSC	Foretinib	1.4634
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	CUDC-101	1.9293
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Pelitinib	64.4233
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Foretinib	0.6063
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	CI-1033	31.2736
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	PF-00299804	19.8499
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	AST-1306	11.7403
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Gefitinib	5.7624
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Afatinib	3.8907
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Cetuximab	601.8601
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	HG-5-88-01	6.8021
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Afatinib	23.0585
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	AZD8931	8.0676
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Gefitinib	10.495
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Afatinib	22.131
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Erlotinib	36.467
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Sapitinib	37.53
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Lapatinib	114.92
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	AZD3759	35.155
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Osimertinib	15.174
SIDM00042	PAAD\|pancreas	p.S1056F (No)	GDSC	Foretinib	3.3078
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	CUDC-101	1.3492
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Pelitinib	9.9577
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Foretinib	2.9404
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	CI-1033	10.9648
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	PF-00299804	184.2009
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	AST-1306	17.2473
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Gefitinib	1.0434
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Afatinib	1.6294
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Cetuximab	559.0506
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Afatinib	47.9957
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	AZD8931	41.8567
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Gefitinib	20.305
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Afatinib	12.164
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Erlotinib	10.829
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Sapitinib	54.924
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Lapatinib	14.387
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	AZD3759	11.369
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Osimertinib	1.4328
SIDM00638	CESC\|cervix	p.S77F (No)	GDSC	Foretinib	4.3636
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	CUDC-101	9.3066
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Pelitinib	18.5625
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Foretinib	2.8306
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	CI-1033	9.3187
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	PF-00299804	4.5029
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	AST-1306	4.1386
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Gefitinib	0.6695
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Afatinib	0.3322
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Cetuximab	78.0416
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	HG-5-88-01	38.4706
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Afatinib	6.408
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	AZD8931	1.2313
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Gefitinib	18.186
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Afatinib	6.903
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Erlotinib	5.6411
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Sapitinib	35.28
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Lapatinib	47.154
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	AZD3759	8.4015
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Osimertinib	4.3704
SIDM00333	UCEC\|endometrium	p.L1049F (No)	GDSC	Foretinib	7.9407
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	Erlotinib	0.9227
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	Lapatinib	0.7484
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	CUDC-101	0.8073
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	Pelitinib	2.0375
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	Foretinib	1.6479
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	CI-1033	2.2192
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	PF-00299804	2.4038
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	AST-1306	1.9084
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	Gefitinib	0.8739
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	Afatinib	0.3017
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	Cetuximab	484.0034
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	HG-5-88-01	96.5463
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	Afatinib	8.2987
SIDM00794	UNCLASSIFIED\|skin_other	p.R832C (No)	GDSC	AZD8931	1.0673
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	CUDC-101	0.7645
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Pelitinib	0.0214
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Foretinib	0.8672
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	CI-1033	0.3348
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	PF-00299804	0.2172
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	AST-1306	0.1719
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Gefitinib	0.0824
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Afatinib	0.0187
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Cetuximab	522.6944
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	HG-5-88-01	12.3977
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Afatinib	0.154
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	AZD8931	0.0966
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Gefitinib	1.2823
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Afatinib	0.2357
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Erlotinib	3.2408
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Sapitinib	0.8851
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Lapatinib	0.3282
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	AZD3759	7.4527
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Osimertinib	0.215
SIDM00530	ESCA\|oesophagus	p.A1048V (No)	GDSC	Foretinib	7.7242
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	CUDC-101	0.2152
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Pelitinib	8.2718
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Foretinib	1.0591
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	CI-1033	26.5982
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	PF-00299804	24.6286
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	AST-1306	24.8067
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Gefitinib	7.2184
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Afatinib	13.08
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	HG-5-88-01	22.6652
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Afatinib	174.1498
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	AZD8931	3.5623
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Gefitinib	65.697
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Afatinib	7.1009
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Erlotinib	47.651
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Sapitinib	128.06
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Lapatinib	148.09
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	AZD3759	16.323
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Osimertinib	35.049
SIDM01101	NB\|neuroblastoma	p.R675Q (No)	GDSC	Foretinib	3.9339
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	CUDC-101	2.1098
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Pelitinib	7.114
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Foretinib	0.7064
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	CI-1033	2.0286
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	PF-00299804	2.3095
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	AST-1306	1.0627
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Gefitinib	6.2841
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Afatinib	1.959
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Cetuximab	728.1536
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	HG-5-88-01	8.5538
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Afatinib	60.0353
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	AZD8931	2.5806
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Gefitinib	33.896
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Afatinib	2.3253
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Erlotinib	19.193
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Sapitinib	85.062
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Lapatinib	12.717
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	AZD3759	19.712
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Osimertinib	3.8707
SIDM00599	UNCLASSIFIED\|osteosarcoma	p.D191Y (No)	GDSC	Foretinib	0.4891
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	CUDC-101	1.26
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Pelitinib	4.7058
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Foretinib	13.9877
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	CI-1033	8.9729
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	PF-00299804	12.1796
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	AST-1306	13.763
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Gefitinib	1.051
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Afatinib	0.6557
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Cetuximab	76.0208
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	HG-5-88-01	176.2698
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Afatinib	19.0787
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	AZD8931	1.9269
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Gefitinib	25.858
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Afatinib	14.632
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Erlotinib	14.035
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Sapitinib	10.062
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Lapatinib	7.572
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	AZD3759	9.4824
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Osimertinib	11.523
SIDM00893	BRCA\|breast	p.G182V (No)	GDSC	Foretinib	15.565
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	CUDC-101	1.0261
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	Pelitinib	23.3161
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	Foretinib	0.4502
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	CI-1033	122.4547
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	PF-00299804	14.2959
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	AST-1306	14.5622
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	Gefitinib	1.5924
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	Afatinib	4.8546
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	Cetuximab	514.0672
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	HG-5-88-01	42.9403
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	Afatinib	11.2975
SIDM00084	GBM\|glioma	p.S1059P (No)	GDSC	AZD8931	6.4326
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Erlotinib	14.4731
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Lapatinib	10.3468
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	CUDC-101	0.1509
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Pelitinib	7.4365
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Foretinib	0.8291
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	CI-1033	147.8495
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	PF-00299804	15.5957
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	AST-1306	56.323
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Gefitinib	4.3002
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Afatinib	4.6328
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Cetuximab	448.0254
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	HG-5-88-01	4.041
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Afatinib	31.9365
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	AZD8931	4.4303
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Gefitinib	16.478
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Afatinib	2.6051
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Erlotinib	11.841
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Sapitinib	52.407
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Lapatinib	3.7427
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	AZD3759	8.4342
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Osimertinib	2.2997
SIDM00993	MM\|haematopoietic_neoplasm_other	p.K209N (No)	GDSC	Foretinib	1.9411
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Erlotinib	16.7089
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Lapatinib	6.5628
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	CUDC-101	0.1646
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Pelitinib	28.7563
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Foretinib	2.0936
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	CI-1033	13.0661
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	PF-00299804	5.5229
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	AST-1306	9.189
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Gefitinib	4.8237
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Afatinib	2.1504
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Cetuximab	575.3048
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	HG-5-88-01	89.052
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Afatinib	89.052
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	AZD8931	2.2873
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Gefitinib	17.812
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Afatinib	6.7133
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Erlotinib	6.1497
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Sapitinib	23.896
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Lapatinib	5.7949
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	AZD3759	7.2107
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Osimertinib	7.0162
SIDM01042	BRCA\|breast	p.E711K (No)	GDSC	Foretinib	1.8701
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	CUDC-101	0.2045
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	Pelitinib	1.5621
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	Foretinib	0.3489
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	CI-1033	2.15
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	PF-00299804	1.4193
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	AST-1306	2.2393
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	Gefitinib	2.9407
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	Afatinib	2.0071
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	Erlotinib	1.9508
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	Sapitinib	3.9331
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	Lapatinib	8.1579
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	AZD3759	1.4594
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	Osimertinib	0.7541
SIDM00216	COREAD\|large_intestine	p.A864V (No)	GDSC	Foretinib	0.4705
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Erlotinib	49.6083
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Lapatinib	26.169
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	CUDC-101	1.5083
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Pelitinib	4.6964
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Foretinib	7.5179
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	CI-1033	17.2884
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	PF-00299804	23.4556
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	AST-1306	29.1208
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Gefitinib	4.9764
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Afatinib	0.3868
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Cetuximab	780.0929
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	HG-5-88-01	86.3117
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Afatinib	4.889
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	AZD8931	7.086
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Gefitinib	4.8299
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Afatinib	0.7878
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Erlotinib	5.5926
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Sapitinib	1.9915
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Lapatinib	5.5618
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	AZD3759	9.6645
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Osimertinib	0.5307
SIDM00282	COREAD\|large_intestine	p.V323I (No)	GDSC	Foretinib	8.0375
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Erlotinib	49.6083
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Lapatinib	26.169
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	CUDC-101	1.5083
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Pelitinib	4.6964
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Foretinib	7.5179
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	CI-1033	17.2884
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	PF-00299804	23.4556
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	AST-1306	29.1208
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Gefitinib	4.9764
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Afatinib	0.3868
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Cetuximab	780.0929
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	HG-5-88-01	86.3117
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Afatinib	4.889
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	AZD8931	7.086
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Gefitinib	4.8299
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Afatinib	0.7878
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Erlotinib	5.5926
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Sapitinib	1.9915
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Lapatinib	5.5618
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	AZD3759	9.6645
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Osimertinib	0.5307
SIDM00282	COREAD\|large_intestine	p.E928G (No)	GDSC	Foretinib	8.0375
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Erlotinib	22.2092
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Lapatinib	7.5586
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	CUDC-101	0.1902
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Pelitinib	2.6592
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Foretinib	0.8652
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	CI-1033	35.7038
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	PF-00299804	7.2388
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	AST-1306	12.0816
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Gefitinib	3.789
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Afatinib	3.0654
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Cetuximab	321.8331
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Afatinib	119.3556
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	AZD8931	13.5211
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Gefitinib	56.98
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Afatinib	4.7426
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Erlotinib	58.68
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Sapitinib	418.62
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Lapatinib	18.288
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	AZD3759	46.581
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Osimertinib	14.714
SIDM00660	COREAD\|large_intestine	p.Q486E (No)	GDSC	Foretinib	1.4128
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Erlotinib	22.2092
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Lapatinib	7.5586
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	CUDC-101	0.1902
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Pelitinib	2.6592
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Foretinib	0.8652
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	CI-1033	35.7038
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	PF-00299804	7.2388
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	AST-1306	12.0816
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Gefitinib	3.789
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Afatinib	3.0654
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Cetuximab	321.8331
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Afatinib	119.3556
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	AZD8931	13.5211
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Gefitinib	56.98
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Afatinib	4.7426
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Erlotinib	58.68
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Sapitinib	418.62
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Lapatinib	18.288
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	AZD3759	46.581
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Osimertinib	14.714
SIDM00660	COREAD\|large_intestine	p.T940A (No)	GDSC	Foretinib	1.4128
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Gefitinib	12.1528
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Afatinib	0.0332
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Cetuximab	610.2075
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	HG-5-88-01	25.5328
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Afatinib	0.1447
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	AZD8931	0.3637
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Gefitinib	7.2769
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Afatinib	0.0063
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Erlotinib	58.583
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Sapitinib	0.2454
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Lapatinib	0.1478
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	AZD3759	5.2875
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Osimertinib	0.0615
SIDM01147	STAD\|stomach	p.S703F (No)	GDSC	Foretinib	8.4262
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	CUDC-101	8.3889
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Pelitinib	18.6095
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Foretinib	0.1888
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	CI-1033	16.5824
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	PF-00299804	20.6704
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	AST-1306	134.413
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Gefitinib	10.0701
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Afatinib	10.0673
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Cetuximab	1428.3997
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Afatinib	79.0592
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	AZD8931	24.427
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Gefitinib	75.088
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Afatinib	9.7808
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Erlotinib	74.029
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Sapitinib	444.38
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Lapatinib	31.443
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	AZD3759	37.868
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Osimertinib	37.233
SIDM00247	STAD\|stomach	p.A1048V (No)	GDSC	Foretinib	0.0338
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	CUDC-101	0.0444
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Pelitinib	0.0606
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Foretinib	5.0664
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	CI-1033	0.1898
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	PF-00299804	0.1492
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Gefitinib	0.0203
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Afatinib	0.0009
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Cetuximab	790.0427
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Afatinib	0.0342
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	AZD8931	0.0646
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Gefitinib	0.0644
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Afatinib	0.0896
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Erlotinib	0.0647
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Lapatinib	3.058
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	AZD3759	0.0737
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Osimertinib	0.0274
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746K (No)	GDSC	Foretinib	3.3466
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	CUDC-101	0.0444
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Pelitinib	0.0606
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Foretinib	5.0664
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	CI-1033	0.1898
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	PF-00299804	0.1492
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Gefitinib	0.0203
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Afatinib	0.0009
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Cetuximab	790.0427
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Afatinib	0.0342
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	AZD8931	0.0646
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Gefitinib	0.0644
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Afatinib	0.0896
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Erlotinib	0.0647
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Lapatinib	3.058
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	AZD3759	0.0737
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Osimertinib	0.0274
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746A (No)	GDSC	Foretinib	3.3466
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	CUDC-101	0.0444
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Pelitinib	0.0606
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Foretinib	5.0664
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	CI-1033	0.1898
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	PF-00299804	0.1492
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Gefitinib	0.0203
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Afatinib	0.0009
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Cetuximab	790.0427
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Afatinib	0.0342
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	AZD8931	0.0646
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Gefitinib	0.0644
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Afatinib	0.0896
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Erlotinib	0.0647
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Lapatinib	3.058
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	AZD3759	0.0737
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Osimertinib	0.0274
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.A750E (No)	GDSC	Foretinib	3.3466
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Erlotinib	10.8487
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Lapatinib	13.8937
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	CUDC-101	27.0005
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Pelitinib	2.235
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Foretinib	2.3558
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	CI-1033	29.6849
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	PF-00299804	9.8614
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	AST-1306	16.0601
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Gefitinib	1.0153
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Afatinib	3.2713
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Cetuximab	617.1715
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Afatinib	44.2476
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	AZD8931	10.823
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Gefitinib	17.732
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Afatinib	5.0929
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Erlotinib	18.798
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Sapitinib	48.713
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Lapatinib	9.3616
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	AZD3759	12.502
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Osimertinib	1.2984
SIDM00329	UNCLASSIFIED\|Hodgkin_lymphoma	p.T1085N (Yes)	GDSC	Foretinib	2.9815
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Erlotinib	16.6304
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Lapatinib	9.6979
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	CUDC-101	0.1962
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Pelitinib	1.7375
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Foretinib	0.8607
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	CI-1033	8.4768
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	PF-00299804	7.4016
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	AST-1306	6.2873
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Gefitinib	1.7359
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Afatinib	2.8991
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Cetuximab	578.5014
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Afatinib	72.2345
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	AZD8931	7.1616
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Gefitinib	26.035
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Afatinib	5.9718
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Erlotinib	53.37
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Sapitinib	68.954
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Lapatinib	36.332
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	AZD3759	30.149
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Osimertinib	5.553
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.S811F (No)	GDSC	Foretinib	2.3568
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	CUDC-101	0.8327
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	Pelitinib	5.7084
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	Foretinib	1.6157
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	CI-1033	28.1201
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	PF-00299804	9.7834
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	AST-1306	27.0046
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	Gefitinib	0.8135
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	Afatinib	2.4503
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	Cetuximab	151.8787
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	Afatinib	18.8261
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	AZD8931	2.0623
SIDM01026	ESCA\|oesophagus	p.A702D (No)	GDSC	Afatinib	1.9922
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	CUDC-101	0.2363
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Pelitinib	0.0672
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Foretinib	1.7749
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	CI-1033	0.1143
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	PF-00299804	0.0699
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	AST-1306	0.3311
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Gefitinib	0.559
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Afatinib	0.1961
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Cetuximab	131.0746
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	HG-5-88-01	41.3087
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Afatinib	13.4359
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	AZD8931	2.244
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Gefitinib	1.0339
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Afatinib	0.0763
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Erlotinib	0.5363
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Sapitinib	0.5398
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Lapatinib	0.4597
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	AZD3759	0.6938
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Osimertinib	0.2383
SIDM00487	COREAD\|large_intestine	p.Q408R (No)	GDSC	Foretinib	4.6287
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	CUDC-101	0.2363
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Pelitinib	0.0672
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Foretinib	1.7749
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	CI-1033	0.1143
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	PF-00299804	0.0699
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	AST-1306	0.3311
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Gefitinib	0.559
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Afatinib	0.1961
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Cetuximab	131.0746
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	HG-5-88-01	41.3087
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Afatinib	13.4359
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	AZD8931	2.244
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Gefitinib	1.0339
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Afatinib	0.0763
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Erlotinib	0.5363
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Sapitinib	0.5398
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Lapatinib	0.4597
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	AZD3759	0.6938
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Osimertinib	0.2383
SIDM00487	COREAD\|large_intestine	p.Y1069C (No)	GDSC	Foretinib	4.6287
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Erlotinib	49.6083
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Lapatinib	26.169
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	CUDC-101	1.5083
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Pelitinib	4.6964
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Foretinib	7.5179
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	CI-1033	17.2884
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	PF-00299804	23.4556
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	AST-1306	29.1208
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Gefitinib	4.9764
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Afatinib	0.3868
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Cetuximab	780.0929
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	HG-5-88-01	86.3117
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Afatinib	4.889
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	AZD8931	7.086
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Gefitinib	4.8299
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Afatinib	0.7878
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Erlotinib	5.5926
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Sapitinib	1.9915
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Lapatinib	5.5618
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	AZD3759	9.6645
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Osimertinib	0.5307
SIDM00282	COREAD\|large_intestine	p.G640fs*3 (No)	GDSC	Foretinib	8.0375
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	CUDC-101	0.6253
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Pelitinib	16.3213
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Foretinib	1.4889
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	CI-1033	13.3391
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	PF-00299804	10.7221
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	AST-1306	5.4999
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Gefitinib	0.61
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Afatinib	0.2114
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Cetuximab	224.849
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	HG-5-88-01	7.9296
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	AZD8931	0.5626
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Gefitinib	3.9855
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Afatinib	1.5508
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Erlotinib	1.4877
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Sapitinib	8.0082
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Lapatinib	13.223
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	AZD3759	2.0345
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Osimertinib	1.3102
SIDM00341	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.L747_P753delinsS (No)	GDSC	Foretinib	1.917
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	CUDC-101	0.9894
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Pelitinib	3.4667
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Foretinib	0.994
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	CI-1033	141.2353
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	PF-00299804	20.4646
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	AST-1306	10.5058
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Gefitinib	1.9873
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Afatinib	10.2298
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Cetuximab	1020.6266
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	HG-5-88-01	13.1948
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Afatinib	152.4086
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	AZD8931	8.8168
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Gefitinib	323.96
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Afatinib	111.49
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Erlotinib	41.115
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Sapitinib	713.77
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Lapatinib	1212.2
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	AZD3759	63.905
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Osimertinib	27.633
SIDM00867	GBM\|glioma	p.G682V (No)	GDSC	Foretinib	38.533
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Erlotinib	6.1535
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Lapatinib	11.2983
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	CUDC-101	0.1078
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Pelitinib	3.2673
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Foretinib	0.5605
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	CI-1033	3.7843
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	PF-00299804	3.5609
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	AST-1306	3.2814
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Gefitinib	0.7941
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Afatinib	5.8291
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Cetuximab	651.5271
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Afatinib	99.0163
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	AZD8931	8.3246
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Gefitinib	19.292
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Afatinib	3.1878
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Erlotinib	19.295
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Sapitinib	102.71
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Lapatinib	7.0954
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	AZD3759	9.4032
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Osimertinib	5.8805
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.E257D (No)	GDSC	Foretinib	3.1113
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	CUDC-101	0.0483
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Pelitinib	8.7175
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Foretinib	0.3298
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	CI-1033	6.3592
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	PF-00299804	9.8169
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	AST-1306	9.134
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Gefitinib	1.939
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Afatinib	5.0497
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Cetuximab	419.2746
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	HG-5-88-01	100.3789
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Afatinib	87.2766
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	AZD8931	7.3641
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Gefitinib	31.092
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Afatinib	8.9775
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Erlotinib	19.796
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Sapitinib	142.64
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Lapatinib	41.544
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	AZD3759	18.081
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Osimertinib	3.9737
SIDM01116	UNCLASSIFIED\|lung_NSCLC_large_cell	p.S703F (No)	GDSC	Foretinib	2.1359
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Erlotinib	9.9957
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Lapatinib	23.5704
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	CUDC-101	2.1672
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Pelitinib	7.2735
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Foretinib	0.9206
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	CI-1033	11.0663
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	PF-00299804	8.6738
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	AST-1306	4.3407
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Gefitinib	9.7206
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Afatinib	6.0119
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Cetuximab	430.2051
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	HG-5-88-01	43.3899
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Afatinib	64.89
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	AZD8931	4.4658
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Gefitinib	32.003
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Afatinib	4.8731
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Erlotinib	21.218
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Sapitinib	140.32
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Lapatinib	18.506
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	AZD3759	12.741
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Osimertinib	3.9656
SIDM01112	UNCLASSIFIED\|bone_other	p.S703F (No)	GDSC	Foretinib	3.4928
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	CUDC-101	1.2003
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Pelitinib	0.484
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Foretinib	1.7524
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	CI-1033	2.2926
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	PF-00299804	1.6917
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	AST-1306	1.5865
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Gefitinib	0.5614
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Afatinib	0.333
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Cetuximab	26.8049
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	HG-5-88-01	53.227
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Afatinib	7.9408
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	AZD8931	1.225
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Gefitinib	4.9485
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Afatinib	1.9705
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Erlotinib	4.9131
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Sapitinib	4.1883
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Lapatinib	3.2013
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	AZD3759	2.3021
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Osimertinib	1.6413
SIDM00628	BRCA\|breast	p.S703F (No)	GDSC	Foretinib	2.3916
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	CUDC-101	20.7789
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Pelitinib	1.9066
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Foretinib	121.8592
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	CI-1033	4.9731
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	PF-00299804	8.7254
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	AST-1306	18.0391
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Gefitinib	6.2429
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Afatinib	3.8578
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Cetuximab	190.0273
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	HG-5-88-01	53.7613
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Afatinib	12.0788
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	AZD8931	3.0459
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Gefitinib	16.91
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Afatinib	3.1027
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Erlotinib	3.9146
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Sapitinib	7.8872
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Lapatinib	57.256
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	AZD3759	14.463
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Osimertinib	2.3352
SIDM00114	MESO\|mesothelioma	p.S703F (No)	GDSC	Foretinib	29.013
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Erlotinib	3.1102
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Lapatinib	5.263
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	CUDC-101	0.0491
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Pelitinib	0.2381
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Foretinib	0.3985
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	CI-1033	0.6453
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	PF-00299804	0.9515
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	AST-1306	1.1593
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Gefitinib	2.0313
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Afatinib	1.1253
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Cetuximab	231.9136
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Afatinib	39.899
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	AZD8931	4.3846
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Gefitinib	8.0052
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Afatinib	1.1165
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Erlotinib	8.7266
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Sapitinib	3.324
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Lapatinib	4.182
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	AZD3759	2.4089
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Osimertinib	1.4614
SIDM00407	DLBC\|B_cell_lymphoma	p.V738D (No)	GDSC	Foretinib	0.8669
SIDM00055	LUAD\|lung_NSCLC_adenocarcinoma	p.S703F (No)	GDSC	CUDC-101	2.8396
SIDM00055	LUAD\|lung_NSCLC_adenocarcinoma	p.S703F (No)	GDSC	Pelitinib	33.9389
SIDM00055	LUAD\|lung_NSCLC_adenocarcinoma	p.S703F (No)	GDSC	Foretinib	1.4924
SIDM00055	LUAD\|lung_NSCLC_adenocarcinoma	p.S703F (No)	GDSC	CI-1033	9.7052
SIDM00055	LUAD\|lung_NSCLC_adenocarcinoma	p.S703F (No)	GDSC	PF-00299804	9.8433
SIDM00055	LUAD\|lung_NSCLC_adenocarcinoma	p.S703F (No)	GDSC	AST-1306	3.9018
SIDM00055	LUAD\|lung_NSCLC_adenocarcinoma	p.S703F (No)	GDSC	Gefitinib	1.1793
SIDM00055	LUAD\|lung_NSCLC_adenocarcinoma	p.S703F (No)	GDSC	Afatinib	1.3787
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Erlotinib	22.7575
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Lapatinib	23.1804
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	CUDC-101	0.0856
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Pelitinib	3.0708
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Foretinib	1.3415
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	CI-1033	4.9793
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	PF-00299804	3.0583
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	AST-1306	4.9432
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Gefitinib	1.3595
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Afatinib	6.91
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Cetuximab	622.3932
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Afatinib	106.1189
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	AZD8931	107.1974
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Gefitinib	32.086
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Afatinib	3.8083
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Erlotinib	8.3613
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Sapitinib	33.753
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Lapatinib	8.54
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	AZD3759	11.245
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Osimertinib	10.832
SIDM01154	ALL\|lymphoblastic_T_cell_leukaemia	p.C251Y (No)	GDSC	Foretinib	2.078
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	CUDC-101	5.9109
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Pelitinib	8.9908
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Foretinib	0.3739
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	CI-1033	2.6788
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	PF-00299804	2.0828
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	AST-1306	5.0962
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Gefitinib	8.6893
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Afatinib	3.2593
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Cetuximab	752.4511
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Afatinib	65.6414
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	AZD8931	11.1635
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Gefitinib	22.595
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Afatinib	4.44
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Erlotinib	31.859
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Sapitinib	38.305
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Lapatinib	5.4381
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	AZD3759	31.987
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Osimertinib	5.1575
SIDM00855	UNCLASSIFIED\|soft_tissue_other	p.S703F (No)	GDSC	Foretinib	0.3083
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	CUDC-101	0.2076
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Pelitinib	1.2037
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Foretinib	14.4091
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	CI-1033	4.5602
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	PF-00299804	3.4255
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	AST-1306	2.303
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Gefitinib	1.163
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Afatinib	1.5259
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Cetuximab	483.0311
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Afatinib	6.6446
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	AZD8931	3.2673
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Gefitinib	18.633
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Afatinib	2.8554
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Erlotinib	9.3232
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Sapitinib	5.633
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Lapatinib	11.894
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	AZD3759	6.2162
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Osimertinib	2.4625
SIDM00528	BRCA\|breast	p.T678M (No)	GDSC	Foretinib	4.0007
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	CUDC-101	95.6337
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Pelitinib	2.3153
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Foretinib	3.3566
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	CI-1033	0.679
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	PF-00299804	0.5715
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	AST-1306	0.8778
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Gefitinib	3.3981
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Afatinib	0.3571
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Cetuximab	14.0064
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	HG-5-88-01	26.8917
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Afatinib	0.5483
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	AZD8931	0.11
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Gefitinib	2.7112
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Afatinib	1.6077
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Erlotinib	1.1908
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Sapitinib	1.9455
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Lapatinib	13.173
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	AZD3759	2.7716
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Osimertinib	2.021
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.R135K (No)	GDSC	Foretinib	34.948
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	CUDC-101	95.6337
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Pelitinib	2.3153
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Foretinib	3.3566
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	CI-1033	0.679
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	PF-00299804	0.5715
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	AST-1306	0.8778
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Gefitinib	3.3981
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Afatinib	0.3571
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Cetuximab	14.0064
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	HG-5-88-01	26.8917
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Afatinib	0.5483
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	AZD8931	0.11
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Gefitinib	2.7112
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Afatinib	1.6077
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Erlotinib	1.1908
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Sapitinib	1.9455
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Lapatinib	13.173
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	AZD3759	2.7716
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Osimertinib	2.021
SIDM00750	LUAD\|lung_NSCLC_adenocarcinoma	p.D1127N (No)	GDSC	Foretinib	34.948
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	CUDC-101	0.5963
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Pelitinib	0.0947
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Foretinib	2.4713
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	CI-1033	189.7676
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	PF-00299804	85.3776
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	AST-1306	15.4504
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Gefitinib	1.7075
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Afatinib	0.3076
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Cetuximab	33.3048
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	HG-5-88-01	50.0353
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Afatinib	6.1819
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	AZD8931	2.0856
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Gefitinib	7.7082
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Afatinib	1.9758
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Erlotinib	3.768
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Sapitinib	11.668
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Lapatinib	16.164
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	AZD3759	6.1029
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Osimertinib	2.7218
SIDM01103	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.A207V (No)	GDSC	Foretinib	4.6284
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Erlotinib	2.598
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Lapatinib	10.4487
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	CUDC-101	18.7807
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Pelitinib	62.0767
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Foretinib	8.3899
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	CI-1033	37.5661
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	PF-00299804	23.3403
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	AST-1306	7.9521
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Gefitinib	2.1187
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Afatinib	10.6657
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Cetuximab	120.0056
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	HG-5-88-01	2.9428
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Afatinib	14.2921
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	AZD8931	2.4508
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Gefitinib	115.33
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Afatinib	21.26
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Erlotinib	20.577
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Sapitinib	29.377
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Lapatinib	182.78
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	AZD3759	27.628
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Osimertinib	21.732
SIDM00645	LUAD\|lung_NSCLC_adenocarcinoma	p.Q1159H (No)	GDSC	Foretinib	23.473
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Erlotinib	38.594
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Lapatinib	46.4507
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	CUDC-101	0.2522
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Pelitinib	1.2856
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Foretinib	0.3025
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	CI-1033	5.3761
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	PF-00299804	2.8249
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	AST-1306	6.24
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Gefitinib	1.3331
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Afatinib	3.5697
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Cetuximab	794.9029
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	HG-5-88-01	16.2443
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Afatinib	6.1502
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	AZD8931	16.3659
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Gefitinib	25.642
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Afatinib	3.4683
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Erlotinib	10.993
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Sapitinib	48.703
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Lapatinib	21.351
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	AZD3759	13.469
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Osimertinib	3.3018
SIDM00580	LAML\|acute_myeloid_leukaemia	p.A1048V (No)	GDSC	Foretinib	1.5694
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Erlotinib	11.8194
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Lapatinib	17.3313
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	CUDC-101	22.8982
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Pelitinib	5.3664
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Foretinib	1.2978
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	CI-1033	16.5675
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	PF-00299804	18.6261
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	AST-1306	8.8236
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Gefitinib	2.318
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Afatinib	4.7252
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Cetuximab	541.7865
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Afatinib	77.3784
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	AZD8931	7.0735
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Gefitinib	30.023
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Afatinib	5.673
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Erlotinib	11.531
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Sapitinib	148.41
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Lapatinib	11.488
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	AZD3759	9.0659
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Osimertinib	7.2189
SIDM01018	UNCLASSIFIED\|Hodgkin_lymphoma	p.W1157C (No)	GDSC	Foretinib	5.7157
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Erlotinib	43.5992
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Lapatinib	31.6586
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	CUDC-101	0.2312
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Pelitinib	3.6621
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Foretinib	0.5741
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	CI-1033	26.5943
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	PF-00299804	7.2571
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	AST-1306	5.7931
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Gefitinib	0.7661
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Afatinib	5.4512
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Cetuximab	1083.8752
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	HG-5-88-01	4.6109
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Afatinib	30.294
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	AZD8931	5.4301
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Gefitinib	42.751
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Afatinib	2.2157
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Erlotinib	24.328
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Sapitinib	45.403
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Lapatinib	5.62
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	AZD3759	17.545
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Osimertinib	3.5626
SIDM01259	ALL\|lymphoblastic_leukemia	p.C523R (No)	GDSC	Foretinib	1.8666
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Erlotinib	15.4432
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Lapatinib	15.2385
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	CUDC-101	0.0558
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Pelitinib	2.6239
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Foretinib	0.0035
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	CI-1033	0.7557
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	PF-00299804	4.3875
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	AST-1306	5.0071
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Afatinib	0.6381
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Cetuximab	485.8238
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	HG-5-88-01	7.8719
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Afatinib	17.2214
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	AZD8931	1.0985
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Gefitinib	7.8323
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Afatinib	2.2017
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Erlotinib	3.5627
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Sapitinib	4.9607
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Lapatinib	8.0775
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	AZD3759	3.9966
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Osimertinib	0.9883
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.V904I (No)	GDSC	Foretinib	0.003
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	CUDC-101	0.0444
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Pelitinib	0.0606
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Foretinib	5.0664
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	CI-1033	0.1898
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	PF-00299804	0.1492
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Gefitinib	0.0203
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Afatinib	0.0009
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Cetuximab	790.0427
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Afatinib	0.0342
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	AZD8931	0.0646
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Gefitinib	0.0644
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Afatinib	0.0896
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Erlotinib	0.0647
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Lapatinib	3.058
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	AZD3759	0.0737
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Osimertinib	0.0274
SIDM01067	LUAD\|lung_NSCLC_adenocarcinoma	p.E746_A750delELREA (No)	GDSC	Foretinib	3.3466
SIDM00721	SCLC\|lung_small_cell_carcinoma	p.R962H (No)	GDSC	Afatinib	94.037
SIDM00721	SCLC\|lung_small_cell_carcinoma	p.R962H (No)	GDSC	Sapitinib	1261.8
SIDM00390	UNCLASSIFIED\|anaplastic_large_cell_lymphoma	p.R98Q (No)	GDSC	Erlotinib	10.0074
SIDM00390	UNCLASSIFIED\|anaplastic_large_cell_lymphoma	p.R98Q (No)	GDSC	Lapatinib	10.8439
SIDM00390	UNCLASSIFIED\|anaplastic_large_cell_lymphoma	p.R98Q (No)	GDSC	CUDC-101	0.6279
SIDM00390	UNCLASSIFIED\|anaplastic_large_cell_lymphoma	p.R98Q (No)	GDSC	Pelitinib	1.079
SIDM00390	UNCLASSIFIED\|anaplastic_large_cell_lymphoma	p.R98Q (No)	GDSC	Foretinib	0.9202
SIDM00390	UNCLASSIFIED\|anaplastic_large_cell_lymphoma	p.R98Q (No)	GDSC	CI-1033	9.8174
SIDM00390	UNCLASSIFIED\|anaplastic_large_cell_lymphoma	p.R98Q (No)	GDSC	PF-00299804	7.2057
SIDM00390	UNCLASSIFIED\|anaplastic_large_cell_lymphoma	p.R98Q (No)	GDSC	AST-1306	10.81
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Erlotinib	16.5695
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Lapatinib	10.1183
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	CUDC-101	0.1001
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Pelitinib	0.4768
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Foretinib	0.3993
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	CI-1033	2.9775
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	PF-00299804	2.9577
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	AST-1306	3.9355
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Gefitinib	0.7506
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Afatinib	2.4368
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Cetuximab	565.1544
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Afatinib	18.6398
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	AZD8931	68.0415
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Gefitinib	16.154
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Afatinib	3.9323
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Erlotinib	12.225
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Sapitinib	47.775
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Lapatinib	14.749
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	AZD3759	7.4689
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Osimertinib	2.6994
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.G659R (No)	GDSC	Foretinib	1.7114
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	CUDC-101	2.5454
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Pelitinib	382.9437
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Foretinib	10.3013
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	CI-1033	4.7004
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	PF-00299804	5.5519
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	AST-1306	1.9499
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Gefitinib	1.4766
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Afatinib	0.4819
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Cetuximab	55.5342
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Afatinib	5.2813
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	AZD8931	2.6923
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Gefitinib	33.121
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Afatinib	5.8931
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Erlotinib	6.9636
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Sapitinib	7.8343
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Lapatinib	23.341
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	AZD3759	12.087
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Osimertinib	5.4851
SIDM00835	COREAD\|large_intestine	p.V654M (No)	GDSC	Foretinib	3.777
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	CUDC-101	166.7032
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	Pelitinib	130.562
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	Foretinib	207.276
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	CI-1033	12.2259
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	PF-00299804	10.5608
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	AST-1306	4.613
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	Gefitinib	13.683
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	Afatinib	4.275
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	Cetuximab	600.4426
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	HG-5-88-01	15.7471
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	Afatinib	17.5957
SIDM00728	LUAD\|lung_NSCLC_adenocarcinoma	p.V592F (No)	GDSC	AZD8931	25.3386
SIDM00919	OV\|ovary	p.R255Q (No)	GDSC	CUDC-101	1.7339
SIDM00919	OV\|ovary	p.R255Q (No)	GDSC	Pelitinib	3.9629
SIDM00919	OV\|ovary	p.R255Q (No)	GDSC	Foretinib	0.5605
SIDM00919	OV\|ovary	p.R255Q (No)	GDSC	CI-1033	3.8336
SIDM00919	OV\|ovary	p.R255Q (No)	GDSC	PF-00299804	5.8969
SIDM00919	OV\|ovary	p.R255Q (No)	GDSC	AST-1306	2.7584

DegronMD: protein-targeted degradation, mutation and drug response to degrons

Degron: DDTFLPVPEY

Degron related mutations and impact score

Drug responses associated with EGFR mutations

All proteins holding degron of DDTFLPVPEY

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P00533	Epidermal growth factor receptor	DEG_COP1_1	1083:1092	DDTFLPVPEY	COP1	0.9978	More...