DegronMD

Uniprot ID: Q9UK61

Source protein: Protein TASOR

Source gene: TASOR

Class: DEG_APCC_DBOX_1

Location: 464:472

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5865

ASA_SCORE: 32.0111

COIL: 0.3114

CONS_SCORE: 0.7018

DSS_SCORE: 0.0492

HELIX: 0.0061

FCONS_SCORE: 1.2245

RIG_SCORE: 0.8643

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G463E	SIDM01069	Non-Small Cell Lung Carcinoma	GDSC	DRGYLFLLS	DEG_APCC_DBOX_1	0.3056
p.G463E	SIDM00099	Mesothelioma	GDSC	DRGYLFLLS	DEG_APCC_DBOX_1	0.3056
p.K455T	SIDM01611	Endometrial Carcinoma	GDSC	DRGYLFLLS	DEG_APCC_DBOX_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9UK61	Protein TASOR	DEG_APCC_DBOX_1	464:472	DRGYLFLLS	APC,CDC20,FZR1	0.5865	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons