DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
DSGDEIS
Uniprot ID:
Q9UK61
Source protein:
Protein TASOR
Source gene:
TASOR
Class:
DEG_SCF_TRCP1_1
Location:
1510:1516
E3 ligase:
BTRC
DEGRON score:
0.9092
ASA_SCORE:
80.9857
COIL:
0.8476
CONS_SCORE:
0.466
DSS_SCORE:
0.5776
HELIX:
0.1083
FCONS_SCORE:
0.9675
RIG_SCORE:
0.6861
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with TASOR mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of DSGDEIS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9UK61
Protein TASOR
DEG_SCF_TRCP1_1
1510:1516
DSGDEIS
BTRC
0.9092
More...