DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
DSGDFDT
Uniprot ID:
P98088
Source protein:
Mucin-5AC
Source gene:
MUC5AC
Class:
DEG_SCF_TRCP1_1
Location:
1403:1409
E3 ligase:
BTRC
DEGRON score:
0.9872
ASA_SCORE:
48.9857
COIL:
0.7607
CONS_SCORE:
0.3135
DSS_SCORE:
0.4756
HELIX:
0.1004
FCONS_SCORE:
1.0862
RIG_SCORE:
0.724
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with MUC5AC mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of DSGDFDT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P98088
Mucin-5AC
DEG_SCF_TRCP1_1
1403:1409
DSGDFDT
BTRC
0.9872
More...