DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
DSGEGTS
Uniprot ID:
Q8N350
Source protein:
Voltage-dependent calcium channel beta subunit-associated regulatory protein
Source gene:
CBARP
Class:
DEG_SCF_TRCP1_1
Location:
250:256
E3 ligase:
BTRC
DEGRON score:
0.959
ASA_SCORE:
73.4714
COIL:
0.9033
CONS_SCORE:
0.3686
DSS_SCORE:
0.6652
HELIX:
0.0517
FCONS_SCORE:
0.9955
RIG_SCORE:
0.5664
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with CBARP mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of DSGEGTS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8N350
Voltage-dependent calcium channel beta subunit-associated regulatory protein
DEG_SCF_TRCP1_1
250:256
DSGEGTS
BTRC
0.959
More...