DegronMD

Uniprot ID: Q8N8Q3

Source protein: Endonuclease V

Source gene: ENDOV

Class: DEG_SCF_TRCP1_1

Location: 274:279

E3 ligase: BTRC

DEGRON score: 0.5879

ASA_SCORE: 77.1333

COIL: 0.7745

CONS_SCORE: 0.0903

DSS_SCORE: 0.7277

HELIX: 0.1482

FCONS_SCORE: 0.9753

RIG_SCORE: 0.6055

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S279L	TCGA-21-5783	LUSC	TCGA	DSGESS	DEG_SCF_TRCP1_1	0.8778
p.P271S	TCGA-EB-A5UN	SKCM	TCGA	DSGESS	DEG_SCF_TRCP1_1	0.25
p.Q265H	SIDM01269	Esophageal Carcinoma	GDSC	DSGESS	DEG_SCF_TRCP1_1	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8N8Q3	Endonuclease V	DEG_SCF_TRCP1_1	274:279	DSGESS	BTRC	0.5879	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons