DegronMD

Uniprot ID: Q9Y4B6

Source protein: DDB1- and CUL4-associated factor 1

Source gene: DCAF1

Class: DEG_SCF_TRCP1_1

Location: 244:250

E3 ligase: BTRC

DEGRON score: 0.9952

ASA_SCORE: 96.9

COIL: 0.926

CONS_SCORE: 0.2598

DSS_SCORE: 0.5843

HELIX: 0.0476

FCONS_SCORE: 0.893

RIG_SCORE: 0.614

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.H242Y	SIDM01545	Non-Small Cell Lung Carcinoma	GDSC	DSGHKTS	DEG_SCF_TRCP1_1	0.2778
p.D260G	IGROV-1	ovary	COSMIC	DSGHKTS	DEG_SCF_TRCP1_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9Y4B6	DDB1- and CUL4-associated factor 1	DEG_SCF_TRCP1_1	244:250	DSGHKTS	BTRC	0.9952	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons