DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
DSGKNS
Uniprot ID:
Q5T890
Source protein:
DNA excision repair protein ERCC-6-like 2
Source gene:
ERCC6L2
Class:
DEG_SCF_TRCP1_1
Location:
1379:1384
E3 ligase:
BTRC
DEGRON score:
0.8443
ASA_SCORE:
84.9667
COIL:
0.8305
CONS_SCORE:
0
DSS_SCORE:
0.6602
HELIX:
0.1422
FCONS_SCORE:
0
RIG_SCORE:
0.5897
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with ERCC6L2 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of DSGKNS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q5T890
DNA excision repair protein ERCC-6-like 2
DEG_SCF_TRCP1_1
1379:1384
DSGKNS
BTRC
0.8443
More...