DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
DSGLPTT
Uniprot ID:
Q6ZQT7
Source protein:
Putative uncharacterized protein FLJ44672
Source gene:
-
Class:
DEG_SCF_TRCP1_1
Location:
51:57
E3 ligase:
BTRC
DEGRON score:
0.9813
ASA_SCORE:
57.7857
COIL:
0.8474
CONS_SCORE:
0
DSS_SCORE:
0.6228
HELIX:
0.0341
FCONS_SCORE:
0
RIG_SCORE:
0.5963
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of DSGLPTT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q6ZQT7
Putative uncharacterized protein FLJ44672
DEG_SCF_TRCP1_1
51:57
DSGLPTT
BTRC
0.9813
More...