DegronMD

Uniprot ID: Q9Y4C4

Source protein: Malignant fibrous histiocytoma-amplified sequence 1

Source gene: MFHAS1

Class: DEG_SCF_TRCP1_1

Location: 5:11

E3 ligase: BTRC

DEGRON score: 0.9405

ASA_SCORE: 78.9

COIL: 0.571

CONS_SCORE: 0.3631

DSS_SCORE: 0.489

HELIX: 0.0261

FCONS_SCORE: 0.9873

RIG_SCORE: 0.727

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G7C	DO233207	GACA	ICGC	DSGNLKT	DEG_SCF_TRCP1_1	0.76
p.D5G	DO229250	THCA	ICGC	DSGNLKT	DEG_SCF_TRCP1_1	0.7198
p.S6G	ACH-000990	Endometrial/Uterine Cancer	CCLE	DSGNLKT	DEG_SCF_TRCP1_1	0.8104
p.S6G	ACH-001394	Breast Cancer	CCLE	DSGNLKT	DEG_SCF_TRCP1_1	0.8104

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9Y4C4	Malignant fibrous histiocytoma-amplified sequence 1	DEG_SCF_TRCP1_1	5:11	DSGNLKT	BTRC	0.9405	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons