DegronMD

Uniprot ID: P35368

Source protein: Alpha-1B adrenergic receptor

Source gene: ADRA1B

Class: DEG_SCF_TRCP1_1

Location: 469:475

E3 ligase: BTRC

DEGRON score: 0.9504

ASA_SCORE: 53.4429

COIL: 0.5911

CONS_SCORE: 0.1996

DSS_SCORE: 0.6051

HELIX: 0.1003

FCONS_SCORE: 1.0699

RIG_SCORE: 0.6861

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R467H	ACH-000820	Colon/Colorectal Cancer	CCLE	DSGPLFT	DEG_SCF_TRCP1_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P35368	Alpha-1B adrenergic receptor	DEG_SCF_TRCP1_1	469:475	DSGPLFT	BTRC	0.9504	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons