DegronMD

Uniprot ID: Q9GZV1

Source protein: Ankyrin repeat domain-containing protein 2

Source gene: ANKRD2

Class: DEG_SCF_TRCP1_1

Location: 348:353

E3 ligase: BTRC

DEGRON score: 0.8206

ASA_SCORE: 75.4167

COIL: 0.8192

CONS_SCORE: 0.4322

DSS_SCORE: 0.9176

HELIX: 0.0428

FCONS_SCORE: 0.9547

RIG_SCORE: 0.5327

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E352Q	TCGA-DK-AA6S	BLCA	TCGA	DSGRET	DEG_SCF_TRCP1_1	0.5633
p.A359V	TCGA-EB-A85J	SKCM	TCGA	DSGRET	DEG_SCF_TRCP1_1	0.1667
p.G345E	TCGA-XF-A9T5	BLCA	TCGA	DSGRET	DEG_SCF_TRCP1_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9GZV1	Ankyrin repeat domain-containing protein 2	DEG_SCF_TRCP1_1	348:353	DSGRET	BTRC	0.8206	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons