DegronMD

Uniprot ID: Q6PIU1

Source protein: Potassium voltage-gated channel subfamily V member 1

Source gene: KCNV1

Class: DEG_SCF_TRCP1_1

Location: 14:20

E3 ligase: BTRC

DEGRON score: 0.563

ASA_SCORE: 73

COIL: 0.8383

CONS_SCORE: 0.2467

DSS_SCORE: 0.36

HELIX: 0.1161

FCONS_SCORE: 1.0031

RIG_SCORE: 0.6543

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D14H	DO217818	GACA	ICGC	DSGSLTS	DEG_SCF_TRCP1_1	0.7688
p.A7E	DO232038	ORCA	ICGC	DSGSLTS	DEG_SCF_TRCP1_1	0.1389
p.S11T	DO38847	STAD	ICGC	DSGSLTS	DEG_SCF_TRCP1_1	0.25
p.R6I	SIDM01277	Esophageal Carcinoma	GDSC	DSGSLTS	DEG_SCF_TRCP1_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q6PIU1	Potassium voltage-gated channel subfamily V member 1	DEG_SCF_TRCP1_1	14:20	DSGSLTS	BTRC	0.563	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons