DegronMD

Uniprot ID: O96028

Source protein: Histone-lysine N-methyltransferase NSD2

Source gene: NSD2

Class: DEG_SCF_SKP2-CKS1_1

Location: 540:547

E3 ligase: SKP2,CSK1

DEGRON score: 0.9752

ASA_SCORE: 103.75

COIL: 0.5993

CONS_SCORE: 0.3272

DSS_SCORE: 0.6827

HELIX: 0.3786

FCONS_SCORE: 1.1634

RIG_SCORE: 0.687

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T551M	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	EAEDTPRK	DEG_SCF_SKP2-CKS1_1	0.2222

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O96028	Histone-lysine N-methyltransferase NSD2	DEG_SCF_SKP2-CKS1_1	540:547	EAEDTPRK	SKP2,CSK1	0.9752	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons