DegronMD

Uniprot ID: Q9UPI3

Source protein: Feline leukemia virus subgroup C receptor-related protein 2

Source gene: FLVCR2

Class: DEG_COP1_1

Location: 509:520

E3 ligase: COP1

DEGRON score: 0.7728

ASA_SCORE: 101.2333

COIL: 0.7674

CONS_SCORE: 0.2589

DSS_SCORE: 0.7142

HELIX: 0.2156

FCONS_SCORE: 1.0678

RIG_SCORE: 0.6439

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.N503Y	TCGA-29-2434	OV	TCGA	EEESNTSKVPTA	DEG_COP1_1	0.1667
p.N503Y	DO31360	OV	ICGC	EEESNTSKVPTA	DEG_COP1_1	0.1667
p.E499G	TCGA-B5-A1MR	UCEC	TCGA	EEESNTSKVPTA	DEG_COP1_1	0.0556
p.E499G	DO41758	UCEC	ICGC	EEESNTSKVPTA	DEG_COP1_1	0.0556
p.E502D	DO36556	READ	ICGC	EEESNTSKVPTA	DEG_COP1_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9UPI3	Feline leukemia virus subgroup C receptor-related protein 2	DEG_COP1_1	509:520	EEESNTSKVPTA	COP1	0.7728	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons