DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
EEGNDSEEVPEA
Uniprot ID:
Q16385
Source protein:
Protein SSX2
Source gene:
SSX2; SSX2B
Class:
DEG_COP1_1
Location:
118:129
E3 ligase:
COP1
DEGRON score:
0.581
ASA_SCORE:
100.55
COIL:
0.8475
CONS_SCORE:
0.5066
DSS_SCORE:
0.8121
HELIX:
0.1184
FCONS_SCORE:
0.9232
RIG_SCORE:
0.578
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SSX2; SSX2B mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of EEGNDSEEVPEA
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q16385
Protein SSX2
DEG_COP1_1
118:129
EEGNDSEEVPEA
COP1
0.581
More...