DegronMD

Uniprot ID: A6NJT0

Source protein: Homeobox protein unc-4 homolog

Source gene: UNCX

Class: DEG_COP1_1

Location: 504:514

E3 ligase: COP1

DEGRON score: 0.7693

ASA_SCORE: 81.8636

COIL: 0.9073

CONS_SCORE: 0.227

DSS_SCORE: 0.8144

HELIX: 0.0585

FCONS_SCORE: 0.9918

RIG_SCORE: 0.5482

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R498W	DO856	BLCA	ICGC	EEPATCGVPEP	DEG_COP1_1	0.1667
p.P500S	DO46783	PAEN	ICGC	EEPATCGVPEP	DEG_COP1_1	0.2222
p.P502A	SIDM00769	Non-Small Cell Lung Carcinoma	GDSC	EEPATCGVPEP	DEG_COP1_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
A6NJT0	Homeobox protein unc-4 homolog	DEG_COP1_1	504:514	EEPATCGVPEP	COP1	0.7693	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons