DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
EPYTVAPVPDM
Uniprot ID:
A6NE52
Source protein:
WD repeat-containing protein 97
Source gene:
WDR97
Class:
DEG_COP1_1
Location:
1513:1523
E3 ligase:
COP1
DEGRON score:
0.9887
ASA_SCORE:
77.1545
COIL:
0.8791
CONS_SCORE:
0.2932
DSS_SCORE:
0.5513
HELIX:
0.0305
FCONS_SCORE:
0.8888
RIG_SCORE:
0.6495
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with WDR97 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of EPYTVAPVPDM
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NE52
WD repeat-containing protein 97
DEG_COP1_1
1513:1523
EPYTVAPVPDM
COP1
0.9887
More...