DegronMD

Uniprot ID: Q504Y2

Source protein: Extracellular tyrosine-protein kinase PKDCC

Source gene: PKDCC

Class: DEG_APCC_DBOX_1

Location: 83:91

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5709

ASA_SCORE: 91.5333

COIL: 0.665

CONS_SCORE: 0.3736

DSS_SCORE: 0.7216

HELIX: 0.2207

FCONS_SCORE: 1.2346

RIG_SCORE: 0.6873

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G96D	DO228904	LICA	ICGC	ERRRLMDLA	DEG_APCC_DBOX_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q504Y2	Extracellular tyrosine-protein kinase PKDCC	DEG_APCC_DBOX_1	83:91	ERRRLMDLA	APC,CDC20,FZR1	0.5709	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons