DegronMD

Uniprot ID: Q96GP6

Source protein: Scavenger receptor class F member 2

Source gene: SCARF2

Class: DEG_COP1_1

Location: 574:583

E3 ligase: COP1

DEGRON score: 0.9399

ASA_SCORE: 80.64

COIL: 0.891

CONS_SCORE: 0.2985

DSS_SCORE: 0.7187

HELIX: 0.075

FCONS_SCORE: 0.7069

RIG_SCORE: 0.6286

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R571Q	DO233941	GACA	ICGC	ESRDPEVPTV	DEG_COP1_1	0.25
p.R571Q	DO230449	UTCA	ICGC	ESRDPEVPTV	DEG_COP1_1	0.25
p.E579K	DO36556	READ	ICGC	ESRDPEVPTV	DEG_COP1_1	0.591
p.A584V	DO41199	UCEC	ICGC	ESRDPEVPTV	DEG_COP1_1	0.3056
p.S591A	ACH-000192	Endometrial/Uterine Cancer	CCLE	ESRDPEVPTV	DEG_COP1_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96GP6	Scavenger receptor class F member 2	DEG_COP1_1	574:583	ESRDPEVPTV	COP1	0.9399	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons