DegronMD

Uniprot ID: Q15013

Source protein: MAD2L1-binding protein

Source gene: MAD2L1BP

Class: DEG_COP1_1

Location: 7:17

E3 ligase: COP1

DEGRON score: 0.6611

ASA_SCORE: 70.4273

COIL: 0.6846

CONS_SCORE: 0.3007

DSS_SCORE: 0.4714

HELIX: 0.2615

FCONS_SCORE: 0.8196

RIG_SCORE: 0.7421

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A3V	DO10582	COAD	ICGC	EVLSSAAVPDL	DEG_COP1_1	0.6667
p.P5L	SIDM02028	Esophageal Carcinoma	GDSC	EVLSSAAVPDL	DEG_COP1_1	0.2778
p.E5G	ACH-001518	Endometrial/Uterine Cancer	CCLE	EVLSSAAVPDL	DEG_COP1_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q15013	MAD2L1-binding protein	DEG_COP1_1	7:17	EVLSSAAVPDL	COP1	0.6611	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons