DegronMD

Uniprot ID: O15037

Source protein: Protein KHNYN

Source gene: KHNYN

Class: LIG_APCC_ABBA_1

Location: 319:324

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.775

ASA_SCORE: 94.05

COIL: 0.7742

CONS_SCORE: 0.3938

DSS_SCORE: 0.4074

HELIX: 0.0343

FCONS_SCORE: 0.8836

RIG_SCORE: 0.7095

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R334S	DO228931	LICA	ICGC	FCVHRE	LIG_APCC_ABBA_1	0.0556
p.G330V	DO229015	LICA	ICGC	FCVHRE	LIG_APCC_ABBA_1	0.1667
p.G330C	DO229036	LICA	ICGC	FCVHRE	LIG_APCC_ABBA_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O15037	Protein KHNYN	LIG_APCC_ABBA_1	319:324	FCVHRE	APC,CDC20,FZR1	0.775	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons