DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
FRASLTKME
Uniprot ID:
Q9UF83
Source protein:
Uncharacterized protein DKFZp434B061
Source gene:
-
Class:
DEG_APCC_DBOX_1
Location:
32:40
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.8802
ASA_SCORE:
113.7
COIL:
0.9078
CONS_SCORE:
0.3766
DSS_SCORE:
0.5218
HELIX:
0.0652
FCONS_SCORE:
0.9157
RIG_SCORE:
0.7438
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of FRASLTKME
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9UF83
Uncharacterized protein DKFZp434B061
DEG_APCC_DBOX_1
32:40
FRASLTKME
APC,CDC20,FZR1
0.8802
More...