DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
FTVHAD
Uniprot ID:
Q58FF7
Source protein:
Putative heat shock protein HSP 90-beta-3
Source gene:
HSP90AB3P
Class:
LIG_APCC_ABBA_1
Location:
144:149
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.8563
ASA_SCORE:
49.8333
COIL:
0.2405
CONS_SCORE:
0.5708
DSS_SCORE:
0.5027
HELIX:
0.0062
FCONS_SCORE:
0.9963
RIG_SCORE:
0.7003
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with HSP90AB3P mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of FTVHAD
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q58FF7
Putative heat shock protein HSP 90-beta-3
LIG_APCC_ABBA_1
144:149
FTVHAD
APC,CDC20,FZR1
0.8563
More...