DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
FYPFQE
Uniprot ID:
Q3C1V9
Source protein:
Putative uncharacterized protein ENSP00000334305
Source gene:
-
Class:
LIG_APCC_ABBA_1
Location:
42:47
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9947
ASA_SCORE:
76.9
COIL:
0.77
CONS_SCORE:
0
DSS_SCORE:
0.3922
HELIX:
0.1212
FCONS_SCORE:
0
RIG_SCORE:
0.7786
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of FYPFQE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q3C1V9
Putative uncharacterized protein ENSP00000334305
LIG_APCC_ABBA_1
42:47
FYPFQE
APC,CDC20,FZR1
0.9947
More...